Haematologica
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Haematologica, Vol 80, Issue 5, 434-436
Copyright © 1995 by Ferrata Storti Foundation


Case Reports

Trisomy 13 in a case of myelofibrosis with myeloid metaplasia with early blastic transformation

F Ferrara, L Vicari, B Festa, R Di Noto, F Pane, L Sebastio, and R Cimino

Divisione di Ematologia, Ospedale Cardarelli, Naples, Italy.

We describe a case of early myeloid blastic transformation in a 64-year-old man suffering from myelofibrosis with myeloid metaplasia. Both chronic and blastic phase cytogenetic analysis showed trisomy 13 to be the sole chromosome aberration. A potential role for this rare abnormality in determining such an unusually poor clinical outcome is discussed.





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Copyright © 1995 by the Ferrata Storti Foundation.