Haematologica
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Haematologica, Vol 80, Issue 6, 526-528
Copyright © 1995 by Ferrata Storti Foundation

Case Reports

Translocation t(8;22) and monosomy 7 in a case of acute lymphoblastic leukemia expressing myeloid markers

E Pedrazzini, SC Goldztein, G Shilton, and I Slavutsky

Departamento de Ciencias Biologicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Buenos Aires, Argentina.

The simultaneous coexpression of lymphoid and myeloid markers has been observed in some cases of childhood acute lymphoblastic leukemias (ALL). In this paper, we describe a 6-year-old male patient with an ALL expressing myeloid antigens in whom a novel karyotypic association, t(8;22) and monosomy 7, and high Ag-NOR activity were found concomitantly with a very short survival.




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Copyright © 1995 by the Ferrata Storti Foundation.