Haematologica
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Haematologica, Vol 88, Issue 11, 1317-1320
Copyright © 2003 by Ferrata Storti Foundation

Letter

Cell lineage assignment of cytogenetic findings in acute lymphoblastic leukemia using combined immunomagnetic cell separation and chromosome preparation

H Rieder, I Bachmann, S Busch, S Schwartz, B Reckzeh, and D Hoelzer

In acute lymphoblastic leukemia (ALL) abnormal karyotypes frequently constitute a minor part of the dividing cells, and the origin of metaphases in normal diploid cases remains obscure. We used a combination of immunomagnetic cell separation and chromosome preparation (ICSCP) to focus on the metaphases of interest and to assign the chromosome findings to CD19+ or CD7+ leukemia cells.




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Copyright © 2003 by the Ferrata Storti Foundation.