Haematologica, Vol 89, Issue 11, 1389-1391
Copyright © 2004 by Ferrata Storti Foundation
A pilot study on the efficacy of ketorolac plus tramadol infusion combined with erythrocytapheresis in the management of acute severe vaso-occlusive crises and sickle cell pain
L de Franceschi,
G Finco,
A Vassanelli,
B Zaia,
S Ischia,
and
R Corrocher
One of the major causes of hospitalization for patients with sickle cell disease (SCD) are vaso-occlusive crises (VOC), which are characterized by acute pain and organ damage related to the presence of dense red cells. Here we report a pilot study which combined balanced analgesia with tramadol plus ketorolac and erythrocytapheresis. Key words: sickle cell disease, therapeutic erythrocytapheresis, HbS, visual analog scale, vaso-occlusive crisis.