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Haematologica, Vol 89, Issue 3, 378-380
Copyright © 2004 by Ferrata Storti Foundation

Letter

Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic malignancies

Y Myoken, T Kyo, M Fujihara, T Sugata, and Y Mikami

A 5-year retrospective analysis of fungemia in patients with hematologic malignancies revealed that four patients, who received fluconazole and itraconazole during neutropenia, developed breakthrough candidemia due to azole-resistant Candida tropicalis isolates. This observation suggests that causative organisms of candidemia in neutropenic patients receiving azoles should be suspected of being azole-resistant.


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