Haematologica, Vol 89, Issue 5, 608-609
Copyright © 2004 by Ferrata Storti Foundation
Mass spectrometry and DNA sequencing are complementary techniques for characterizing hemoglobin variants: the example of hemoglobin J-Oxford
D Caruso,
M Crestani,
L Da Riva,
N Mitro,
F Giavarini,
R Mozzi,
and
C Franzini
Liquid chromatography-electrospray ionization-mass spectrometry (MS) allows the characterization of most hemoglobin variants and can sometimes be a useful tool to narrow down DNA sequencing analysis. As an example, we report a case of hemoglobin variant J-Oxford, characterized by MS and DNA sequencing analysis.