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Haematologica, Vol 89, Issue 5, 608-609
Copyright © 2004 by Ferrata Storti Foundation


Letter

Mass spectrometry and DNA sequencing are complementary techniques for characterizing hemoglobin variants: the example of hemoglobin J-Oxford

D Caruso, M Crestani, L Da Riva, N Mitro, F Giavarini, R Mozzi, and C Franzini

Liquid chromatography-electrospray ionization-mass spectrometry (MS) allows the characterization of most hemoglobin variants and can sometimes be a useful tool to narrow down DNA sequencing analysis. As an example, we report a case of hemoglobin variant J-Oxford, characterized by MS and DNA sequencing analysis.





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