Haematologica
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Haematologica, Vol 89, Issue 5, 628-629
Copyright © 2004 by Ferrata Storti Foundation

Letter

Xenobiotic gene polymorphisms and susceptibility to multiple myeloma

LF Lincz, I Kerridge, FE Scorgie, M Bailey, A Enno, and A Spencer

Genetic variations in the activity of xenobiotic enzymes may predict susceptibility to multiple myeloma (MM). In a case-control study, 90 Australian Caucasians with MM had significantly higher incidences of GST T1 null, PON1 BB and NAT2 slow acetylation genotypes, but no difference in polymorphism frequencies for GST M1, NAT1, and CYP1A1 when compared to 205 controls.




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Copyright © 2004 by the Ferrata Storti Foundation.