Haematologica, Vol 89, Issue 6, 746-747
Copyright © 2004 by Ferrata Storti Foundation
The molecular basis of beta-thalassemia in Argentina. Influence of the pattern of immigration from the Mediterranean Basin
LC Rossetti,
HM Targovnik,
and
V Varela
In order to determine the molecular heterogeneity of the beta-thalassemia gene and to analyze the influence of immigration from the Mediterranean Basin, a total of 254 families (475 subjects) from Argentinean beta-thalassemia patients were investigated using molecular biology techniques. This allowed us to provide a simplified diagnosis and genetic counselling of this disorder in Argentina.