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Haematologica, Vol 89, Issue 6, 755-756
Copyright © 2004 by Ferrata Storti Foundation

Letter

CD45RA+ and CD45RO+ lymphocyte subpopulations in patients with monoclonal gammopathies: correlations with diagnosis, clinical stage and treatment status

JM Raya Sanchez, LH Nieto, ML Brito Barroso, G Gonzalez Brito, and M del Mar Caballero Gomez

Alterations in blood lymphocyte subsets may be involved in the development of overt myeloma. Naive (CD4+CD45RA+) and memory (CD4+CD45RO+) helper T-cell subsets are important effectors of immune T-cell regulation. We analyzed the distribution of these blood lymphocyte subpopulations in patients with monoclonal gammopathies, considering the type of disorder, clinical stage, and treatment status.




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Copyright © 2004 by the Ferrata Storti Foundation.