Haematologica, Vol 90, Issue 11, 1582-1584
Copyright © 2005 by Ferrata Storti Foundation
Development of functional Haemophilus influenzae type b antibodies after vaccination
AM van der Velden,
AM Claessen,
H van Velzen-Blad,
DH Biesma,
and
GT Rijker
Sixteen autologous stem cell transplant recipients received three vaccinations with conjugated haemophilus influenzae type b vaccine. Quantitative and qualitative aspects of the antibody response were studied. The vaccination schedule resulted in high antibody response rates and functional maturation of antibodies, as measured by antibody avidity and phagocytosis-inducing capacity.