Haematologica, Vol 90, Issue 12, 1693-1694
Copyright © 2005 by Ferrata Storti Foundation
Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Jordan
NS Karadsheh,
L Moses,
SI Ismail,
JM Devaney,
and
E Hoffman
Molecular screening for glucose-6-phosphate (G6PD) mutations in two Jordanian populations revealed six different mutations and higher incidences of G6PD deficiency and G6PD A- (376A-->G + 202G-->A) mutation in Jordan Valley than in the Amman area. These observations may be explained by historically higher rates of malaria and African ancestral origins, respectively.
