Haematologica
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Haematologica, Vol 90, Issue 12, 1723-1724
Copyright © 2005 by Ferrata Storti Foundation

Comparative Study

Minor histocompatibility antigen HA-8 mismatch and clinical outcome after HLA-identical sibling donor allogeneic stem cell transplantation

A Perez-Garcia, R De la Camara, A Torres, M Gonzalez, A Jimenez, and D Gallardo

We analyzed the clinical outcome of 146 adult patients receiving an HLA-identical sibling donor stem cell transplant depending on HA-8 matching status. The presence of an HA-8 mismatch was associated with an increased risk of severe acute graft-versus-host disease and with a worse overall survival.


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