Haematologica
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Haematologica, Vol 90, Issue 12_Suppl, ECR39-ECR39
Copyright © 2005 by Ferrata Storti Foundation

Case Reports

Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B

L Vazquez, JJ Mateos, C Sanz-Rodriguez, E Perez, D Caballero, and JF San Miguel

Servicio de Hematologia, Hospital Universitario, Salamanca, Spain. lvazlo@usal.es

Genera of the order Mucorales (Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Cunninghamella, and Saksenaea) cause an angioinvasive infection called zygomycosis. Mortality rates can approach 100% depending on the patient's underlying disease and form of zygomycosis. We report here on the unusual case of a patient with acute myelogenous leukemia and zygomycosis unresponsive to monotherapy with liposomal amphotericin B, who responded favorably following the addition of the echinocandin caspofungin acetate.




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Copyright © 2005 by the Ferrata Storti Foundation.