Haematologica
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Haematologica, Vol 90, Issue 12_Suppl, ECR44-ECR44
Copyright © 2005 by Ferrata Storti Foundation

Journal Article

Skin lesions induced by bortezomib

L Pour, R Hajek, A Zdenek, M Krejci, A Krivanova, and J Vorlicek

Department of Internal Medicine-Hematooncology , Masaryk University Hospital, Jihlavska 20, Brno, 625 00, Czech Republic. lpour@fnbrno.cz

We report on six cases of skin lesions induced by bortezomib in patients treated for relapsed multiple myeloma. The folliculitis-like rash appeared in the second cycle of bortezomib therapy. Therapy with prednisone led to rapid resolution of the skin lesions. Prednisone 10 mg before each infusion of bortezomib was necessary to prevent recurrence of the rash while antihistamines alone were ineffective.




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Copyright © 2005 by the Ferrata Storti Foundation.