Haematologica
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Haematologica, Vol 90, Issue 2, 272-273
Copyright © 2005 by Ferrata Storti Foundation

Letter

Seminested polymerase chain reaction and heteroduplex analysis detects the monoclonality of IgH rearrangement in follicular lymphoma patients with high sensitivity

A Oehadian, N Koide, MM Mu, F Hassan, T Yoshida, and T Yokochi

A new method, combining seminested polymerase chain reaction (PCR) with heteroduplex analysis, was utilized to detect follicular lymphoma (FL) cells in peripheral blood. The method, based on the detection of IgH rearrangements in DNA, detected the presence of monoclonal B cells in FL patients with a high frequency.




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Copyright © 2005 by the Ferrata Storti Foundation.