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Haematologica, Vol 90, Issue 2, 281-283
Copyright © 2005 by Ferrata Storti Foundation

Letter

Effect of a single dose of rituximab in chronic immune thrombocytopenic purpura in childhood

T Taube, H Schmid, H Reinhard, A von Stackelberg, and US Overberg

Twenty-two children with immune thrombocytopenic purpura (ITP) with long-lasting thrombocytopenia, adversely affecting their quality of life, were treated with a reduced rituximab regimen in order to eliminate B cells producing anti-platelet antibody. A single dose of rituximab resulted in a response rate similar to that reported for cases in which 4 doses of rituximab were used.


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