Haematologica
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Haematologica, Vol 90, Issue 3, 406-408
Copyright © 2005 by Ferrata Storti Foundation

Letter

Neutrophil polycythemia rubra vera-1 expression in classic and atypical myeloproliferative disorders and laboratory correlates

S Sirhan, TL Lasho, MA Elliott, and A Tefferi

The current study of 153 subjects with both classic and atypical myeloproliferative disorders suggests that neutrophil polycythemia rubra vera-1 (PRV-1) over-expression is a non-specific feature of clonal myeloproliferation that displays significant correlation with leukocyte alkaline phosphatase score. These observations undermine the utility of the PRV-1 assay as a diagnostic test of additional value.




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Copyright © 2005 by the Ferrata Storti Foundation.