Haematologica
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Haematologica, Vol 90, Issue 3, 408-410
Copyright © 2005 by Ferrata Storti Foundation

Letter

Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study

H Gisslinger, M Mullner, I Pabinger, N Heis-Vahidi-Fard, B Gisslinger, A Brichta, T Bachleitner-Hofmann, and C Mannhalter

The association between a prothrombin mutation and the risk of thrombosis was analyzed in 214 patients with polycythemia vera or essential thrombocythemia. The rate for venous thrombotic events was 14.7/100 patient-years in patients with the prothrombin mutation compared to 0.8 in patients without the mutation (rate ratio 17.5).


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S. Navarro, P. Medina, Y. Mira, A. Estelles, P. Villa, F. Ferrando, A. Vaya, R. M. Bertina, and F. Espana
Haplotypes of the EPCR gene, prothrombin levels, and the risk of venous thrombosis in carriers of the prothrombin G20210A mutation
Haematologica, June 1, 2008; 93(6): 885 - 891.
[Abstract] [Full Text] [PDF]


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Copyright © 2005 by the Ferrata Storti Foundation.