Haematologica
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Haematologica, Vol 90, Issue 3, 412-413
Copyright © 2005 by Ferrata Storti Foundation

Letter

Low frequency of exon 3 PTPN11 mutations in adult de novo acute myeloid leukemia. Analysis of a consecutive series of 173 patients

J Nomdedeu, MT Carricondo, A Lasa, G Perea, A Aventin, and J Sierra

A total of 173 samples obtained from adult patients with de novo acute myeloid leukemia (AML) were assayed for exon 3 PTPN11 mutations by single strand conformation polymorphism (SSCP) analysis and direct sequencing. Only three monocytic leukemias had point mutations (1.73%).




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Copyright © 2005 by the Ferrata Storti Foundation.