Haematologica
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Haematologica, Vol 90, Issue 4, 556-558
Copyright © 2005 by Ferrata Storti Foundation

Letter

Clonal cytogenetic abnormalities in patients with chronic myeloid leukemia in complete cytogenetic response to imatinib mesylate

B Espinet, AC Oliveira, C Boque, A Domingo, E Alonso, and F Sole

The emergence of clonal chromosomal abnormalities in Philadelphia-negative cells during treatment with imatinib in patients with Philadelphia-positive chronic myeloid leukemia has been reported. We add information to this issue presenting a series of 29 patients in complete cytogenetic response after imatinib treatment, three of whom developed clonal aberrations.




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Copyright © 2005 by the Ferrata Storti Foundation.