Haematologica
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Haematologica, Vol 90, Issue 4, 559-562
Copyright © 2005 by Ferrata Storti Foundation

Letter

Global real-time quantification/reverse transcription-polymerase chain reaction for detecting proto-oncogenes associated with 14q32 chromosomal translocation in multiple myeloma

E Tajima, M Uranishi, S Iida, H Komatsu, M Nitta, and R Ueda

A global real-time quantitative/reverse transcription-polymerase chain reaction technique for detecting the expression of six 14q32 chromosomal translocation-associated proto-oncogenes in marrow plasma cells was established and applied to myeloma specimens. This technique is an alternative method of detecting 14q32 rearrangements and allows investigation of the relationship between proto-oncogene expression and clinical features.




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Copyright © 2005 by the Ferrata Storti Foundation.