Haematologica, Vol 90, Issue 7, 1001-1003
Copyright © 2005 by Ferrata Storti Foundation
Feasibility of early tapering of cyclosporine following reduced-intensity stem cell transplantation for advanced hematologic or solid malignancies
A Hori,
M Kami,
M Ohnishi,
N Murashige,
R Kojima,
and
Y Takaue
Although some researchers have reported that early tapering of cyclosporine is feasible and beneficial to augment graft-versus-leukemia effects after conventional stem-cell transplantation, there is little information on the feasibility of this strategy following reduced-intensity stem cell transplantation (RIST). We summarized outcomes of 17 patients who underwent early tapering of cyclosporine following RIST from HLA-identical siblings.