Haematologica, Vol 90, Issue 7, 1003-1004
Copyright © 2005 by Ferrata Storti Foundation
New insights into the pathophysiology of gastrointestinal graft-versus-host disease using capsule endoscopy
M Shapira,
SN Adler,
H Jacob,
IB Resnick,
S Slavin,
and
R Or
We investigated gastrointestinal graft-versus-host-disease using capsule endoscopy in patients with abdominal pain and/or diarrhea. We found severe pathology involving most of the gut including loss of villi, ulcerations, narrowing, bleeding and fistula formation. In 2 patients, capsule endoscopy alone established the diagnosis of graft-versus-host-disease. Some ulcerations were associated with cytomegalovirus infection.