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Haematologica, Vol 90, Issue 7, 1003-1004
Copyright © 2005 by Ferrata Storti Foundation


Letter

New insights into the pathophysiology of gastrointestinal graft-versus-host disease using capsule endoscopy

M Shapira, SN Adler, H Jacob, IB Resnick, S Slavin, and R Or

We investigated gastrointestinal graft-versus-host-disease using capsule endoscopy in patients with abdominal pain and/or diarrhea. We found severe pathology involving most of the gut including loss of villi, ulcerations, narrowing, bleeding and fistula formation. In 2 patients, capsule endoscopy alone established the diagnosis of graft-versus-host-disease. Some ulcerations were associated with cytomegalovirus infection.





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