Haematologica, Vol 90, Issue 7, 994-996
Copyright © 2005 by Ferrata Storti Foundation
The effect of subsequent therapies in patients with chronic lymphocytic leukemia previously treated with prednisone and either cladribine or chlorambucil
T Robak,
JZ Blonski,
M Kasznicki,
J Gora-Tybor,
A Dmoszynska,
and
A Skotnicki
We present the long-term follow-up and results of subsequent treatments in patients with chronic lymphocytic leukemia treated initially with cladribine + prednisone or chlorambucil + prednisone in a randomized, cross-over study. We found higher complete and overall responses rates in patients who received cladribine + prednisone as first and second-line treatment but no significant differences in survival.