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Clinical Trial, Phase II |
Between July 2003 and March 2004, nine patients with pretreated mycosis fungoides were enrolled into a phase II trial and were treated with temozolomide. The overall response rate was 33%. Further studies are needed to test the efficacy of temozolomide, alone or in combination in earlier stages of this disease.
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G. Quereux, S. Marques, J.-M. Nguyen, C. Bedane, M. D'incan, O. Dereure, E. Puzenat, A. Claudy, L. Martin, P. Joly, et al. Prospective Multicenter Study of Pegylated Liposomal Doxorubicin Treatment in Patients With Advanced or Refractory Mycosis Fungoides or Sezary Syndrome Arch Dermatol, June 1, 2008; 144(6): 727 - 733. [Abstract] [Full Text] [PDF] |
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