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Haematologica, Vol 91, Issue 10, 1432-1433
Copyright © 2006 by Ferrata Storti Foundation

Comparative Study

Plasma levels of basic fibroblast growth factor and vascular endothelial growth factor and their association with IgVH mutation status in patients with B-cell chronic lymphocytic leukemia

L Smolej, C Andrys, S Pekova, J Schwarz, D Belada, and P Zak

The mutation status of genes encoding the variable region of immunoglobulin heavy chains (IgV(H)) is a strong predictor of disease progression and survival in B-cell chronic lymphocytic leukemia (B-CLL). We investigated whether there is an association between the concentration of both vascular endothelial growth factor and basic fibroblast growth factor and IgV(H) mutation status in 49 untreated B-CLL patients.




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Copyright © 2006 by the Ferrata Storti Foundation.