Haematologica
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Haematologica, Vol 91, Issue 2, 255-257
Copyright © 2006 by Ferrata Storti Foundation

Journal Article

Topical prophylaxis of conjunctivitis induced by high-dose cytosine arabinoside

P Matteucci, C Carlo-Stella, M Di Nicola, M Magni, A Guidetti, M Marchesi, and AM Gianni

Cristina Gandini Medical Oncology Unit, Istituto Nazionale Tumori, Via Venezian, 1 20133 Milano, Italy. paola.matteucci@istitutotumori.mi.it

We investigated the efficacy of dexamethasone plus diclofenac eye drops as prophylaxis for conjunctivitis induced by high-dose (HD) cytarabine (Ara-C). Sixty patients were randomized to receive either dexamethasone (group A, n=29) or dexamethasone plus diclofenac (group B, n=31). Conjunctivitis was experienced by 13/29 (45%) patients in group A, and 4/31 (13%) patients in group B (p




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Copyright © 2006 by the Ferrata Storti Foundation.