Haematologica
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Haematologica, Vol 91, Issue 2, 270-271
Copyright © 2006 by Ferrata Storti Foundation

Letter

Prognostic value of quantitative analysis of WT1 gene transcripts in adult acute lymphoblastic leukemia

L Chiusa, P Francia di Celle, P Campisi, C Ceretto, F Marmont, and A Pich

We quantified Wilm's tumor gene (WT1) using a real time quantitative polymerase chain reaction in 20 adult patients with acute lymphoblastic leukemia at presentation. A WT1 level greater than 906 (median value for the whole series) was a significant predictor of a poor disease-free and overall survival in uni- and multivariate analyses.




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Copyright © 2006 by the Ferrata Storti Foundation.