Haematologica, Vol 91, Issue 2, 272-273
Copyright © 2006 by Ferrata Storti Foundation
Rituximab plus chemotherapy in children with relapsed or refractory CD20-positive B-cell precursor acute lymphoblastic leukemia
A Claviez,
C Eckert,
K Seeger,
A Schrauder,
M Schrappe,
G Henze,
and
A von Stackelberg
We treated three children with relapsed or refractory CD20 positive B-cell precursor acute lymphoblastic leukemia with rituximab in combination with chemotherapy, which produced a decreasing or persistent low positive minimal residual disease load. Two children subsequently underwent allogeneic stem cell transplantation and remain in complete remission at days +399 and +332.