Haematologica
HOME HELP FEEDBACK TABLE OF CONTENTS ARCHIVE SUBSCRIPTIONS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Germano, G
Right arrow Articles by Basso, G
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Germano, G
Right arrow Articles by Basso, G
Haematologica, Vol 91, Issue 5_Suppl, ECR09-ECR09
Copyright © 2006 by Ferrata Storti Foundation

Case Reports

Two consecutive immunophenotypic switches in a child with MLL-rearranged acute lymphoblastic leukemia

G Germano, M Pigazzi, L del Giudice, M Campo Dell'Orto, M Spinelli, A Zangrando, P Paolucci, S Ladogana, and G Basso

Laboratory of Pediatric Onco-Hematology, Department of Pediatrics, University Hospital of Padua, Padua, Italy.

An 18-month-old girl was diagnosed with pre-pre-B ALL/t(4;11) leukemia, which during the treatment and after matched bone marrow transplantation (BMT), underwent two consecutive switches from lymphoid to myeloid lineage and vice versa. The high expression of HOXA9 and FLT3 genes remaining genotypically stable in a leukemia throughout phenotypic switches, suggests that this leukemia may have originated as a common B/myeloid progenitors.




HOME HELP FEEDBACK TABLE OF CONTENTS ARCHIVE SUBSCRIPTIONS
Copyright © 2006 by the Ferrata Storti Foundation.