Haematologica
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Haematologica, Vol 91, Issue 6, 862-863
Copyright © 2006 by Ferrata Storti Foundation

Letter

Combination chemotherapy with cyclophosphamide, thalidomide and dexamethasone for patients with refractory, newly diagnosed or relapsed myeloma

G Sidra, CD Williams, NH Russell, S Zaman, B Myers, and JL Byrne

We evaluated the combination of thalidomide, pulsed dexamethasone and weekly cyclophosphamide (CTD) for the treatment of patients with newly diagnosed, relapsed or VAD-refractory multiple myeloma. We found that this combination was highly effective in inducing responses in all treatment groups with an overall response rate of 83.8%. CTD was well tolerated and did not impair stem cell mobilization.


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