Haematologica, Vol 91, Issue 8, 1145-1146
Copyright © 2006 by Ferrata Storti Foundation
Imatinib preceding allogeneic stem cell transplantation in chronic myeloid leukemia
JB Perz,
JS Khorashad,
D Marin,
JF Apperley,
and
E Olavarria
In 37 adults with chronic myeloid leukemia undergoing allogeneic stem cell transplantation imatinib prior to transplant had no discernible negative impact on 100-day mortality (13%) and severe acute (22%) or extensive chronic graft-versus- host disease (31%). After a median of 203 days (range: 18-1419) overall and progression-free survival rates are 62% and 54%, respectively.