Haematologica
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Haematologica, Vol 92, Issue 1, 141-142 doi:10.3324/haematol.10561
Copyright © 2007 by Ferrata Storti Foundation
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Malignant Lymphomas

Severe pulmonary complications after initial treatment with rituximab for the Asian-variant of intravascular lymphoma

Shang-Ju Wu*, Wen-Chien Chou*,°, Bo-Sheng Ko*, Hwei-Fang Tien*,

* Department of Internal Medicine, National Taiwan University Hospital;
° Department of Laboratory Medicine, National Taiwan University Hospital

Correspondence: Hwei-Fang Tien, MD, PhD, Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Road, Taipei 100, Taiwan. Phone: international +886.2.23123456; Fax: international +886.2.23959583. E-mail: hftd{at}ha.mc.ntu.edu.tw

Rituximab improves response to treatment and outcome for patients with CD20+ B-cell lymphoma. Herein, however, we report the occurrence of severe pulmonary complications shortly after rituximab infusion in three patients with the newly diagnosed Asian variant of intravascular lymphoma. It is suggested that patients with this sub-type of lymphoma are monitored carefully for possible drug reactions during the use of rituximab.

Key words: rituximab, intravascular lymphoma, complications.




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