Haematologica
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Haematologica, Vol 92, Issue 2, 285-286 doi:10.3324/haematol.10358
Copyright © 2007 by Ferrata Storti Foundation
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Thrombosis

The V617F mutation of JAK2 is very uncommon in patients with thrombosis

Angel F. Remacha, Camino Estivill, M. Pilar Sarda, José Mateo, Joan Carles Souto, Carme Canals, Josep Nomdedéu, Jordi Fontcuberta

Department of Hematology, Hospital de Sant Pau, Avda Padre Claret 167, Barcelona 08025, Spain

Correspondence: Angel F. Remacha, Department of Hematology, Hospital de Sant Pau, Avda Padre Claret 167, Barcelona 08025, Spain. Phone: international +34.9.32919290. Fax: international +34.9.32919192. E-mail: aremacha{at}hsp.santpau.es

Given that many cases of thrombosis do not have a clear cause, a myeloproliferative disease could be involved. We investigated the V617F mutation of the JAK2 gene in 295 patients with thrombosis. Only one case was positive. Therefore, the study of this mutation is not necessary in all patients with idiopathic thrombosis.

Key words: JAK2 mutation, idiopathic thrombosis.






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Copyright © 2007 by the Ferrata Storti Foundation.