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Steroid treatment in children with sickle-cell disease

^* Service de Pédiatrie générale, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
^° Service d’Hématologie pédiatrique, Hôpital Robert Debré, Paris, France;
^# Service d’Hématologie, Hôpital Tenon, Paris, France
^@ Service de Pédiatrie générale, Hôpital Necker, Paris, France
^{^} Département d’ Hématologie/Oncologie, Hôpital Universitaire des Enfants Reine Fabiola, Bruxelles, Belgium

Correspondence: Brigitte Bader-Meunier, Service d’Hématologie pédiatrique, Hôpital Robert Debré, Bd Serrurier, 75019 Paris, France. E-mail: brigitte.bader-meunier{at}rdb.ap-hop-paris.fr

Given the controversy concerning the effects of steroids in patients with sickle cell disease (SCD), we evaluated the tolerability of long-term steroid treatment in 16 children with SCD and autoimmune and/or systemic diseases. The steroid treatment was poorly tolerated.