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High loading dose AmBisome^® is efficacious and well tolerated in the management of invasive fungal infection in hematology patients

^* Division of Cancer Sciences and Molecular Pathology, University of Glasgow, Glasgow
^° St James’s University Hospital, Leeds, UK
^# Glasgow Royal Infirmary, Glasgow, UK
^@ Royal Victoria Infirmary, Newcastle Upon Tyne, UK

Correspondence: Lorna A. McLintock, Division of Cancer Sciences and Molecular Pathology, University of Glasgow, 3^rd Floor Queen Elizabeth Building, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 2ER, UK., Phone: international +0141.2111202., Fax: international +0141.2110414.,E-mail: lmclint{at}aol.com

Despite improved supportive care, and the introduction of less toxic lipid-formulations of amphotericin B deoxycholate and other new antifungal agents the mortality from invasive fungal infection (IFI) in hematology patients remains high. New management strategies are therefore required to improve outcome.