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Intracranial hematopoiesis in a patient with aids-related central nervous system lymphoma and severe pancytopenia

¹ Medical Oncology Unit, University Hospital of Parma
² Department of Pathology, University Hospital of Parma
³ Department of Infectious Diseases and Hepatology, University Hospital of Parma

Correspondence to: Antonino Musolino, Medical Oncology Unit, University Hospital of Parma, Parma ITALY, Tel: +39 0521 702660; fax: +39 0521 995448; e-mail: antoninomusolino{at}hotmail.com

The case here reported reflects the difficulty in diagnosing meningeal extramedullary hematopoiesis (EMH), which clinically appeared concomitantly with primary cerebral lymphoma and occurred in a patient with HIV infection and severe pancytopenia. Pancytopenia secondary to HIV infection could be hypothesized as a predisposing factor for the ectopic development of hematopoietic tissue outside the bone marrow. Although rare, intracranial EMH should always be considered in the differential diagnosis of headache and other endocranial hypertension symptoms in patients with chronic bone marrow dysfunction