Haematologica
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Haematologica, Vol 93, Issue 1, 128-131 doi:10.3324/haematol.11661
Copyright © 2008 by Ferrata Storti Foundation
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Malignant Lymphomas

18-F FDG-PET in the staging of lymphocyte-predominant Hodgkin’s disease

Catherine Ansquer1, Thomas Hervouët2, Anne Devillers2, Sophie de Guibert3, Thomas Gastinne4, Steven Le Gouill4, Etienne Garin2, Anne Moreau5, Françoise Kraeber-Bodéré1, Thierry Lamy3,

1 Département de Médecine Nucléaire, CHU de Nantes, Nantes
2 Département de Médecine Nucléaire, Centre Eugène Marquis, Rennes
3 Service d'Hématologie Clinique, Hôpital Pontchaillou, CHU de Rennes
4 Service d'Hématologie Clinique, Hôpital Hôtel Dieu, CHU de Nantes
5 Laboratoire d’Anatomie-Pathologie, Hôpital Hôtel Dieu, CHU de Nantes, France

Correspondence: Thierry Lamy, Service d'Hématologie Clinique, Hôpital Pontchaillou, CHU de Rennes, 35033 Rennes, France. Phone: +33.2.99284292. Fax: +33.2.99284161. E-mail: thierry.lamy{at}univ-rennes1.fr

This bicentric study assessed retrospectively the usefulness of 18 F-FDG-PET in the staging of 31 patients with lymphocyte-predominant Hodgkin’s disease (LPHD). FDG-PET and conventional explorations (CE) were performed for initial disease (n=25) or recurrence (n= 6). All the 68 involved sites were detected by PET including 5 extra-nodal lesions. Only 43 nodal sites (68%) and one splenic focus were detected by CE. PET changed staging in 9 patients (7 upstaged, 2 downstaged) and radiation fields in 3 patients. These results showed the potential role of PET in the staging of LPHD.

Key words: 18F FDG-PET, FDG-PET, CT, lymphocyte-predominant Hodgkin’s disease, staging.






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Copyright © 2008 by the Ferrata Storti Foundation.