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Table of Contents

January 31, 2015 ;  100 (2)

Editorials

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    Tumor-associated macrophages in diffuse large B-cell lymphoma
    Robert Kridel, Christian Steidl, Randy D. Gascoyne
    Haematologica February 2015 100: 143-145; doi:10.3324/haematol.2015.124008
    • Disclosures
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    Inherited thrombocytopenias in the era of personalized medicine
    Patrizia Noris, Carlo L. Balduini
    Haematologica February 2015 100: 145-148; doi:10.3324/haematol.2014.122549
    • Disclosures

Review Article

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    Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicity
    Johannes Oldenburg, Sébastien Lacroix-Desmazes, David Lillicrap
    Haematologica February 2015 100: 149-156; doi:10.3324/haematol.2014.112821
    • Disclosures and Contributions

Articles

Hematopoiesis

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    In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis
    Stijn Vanhee, Katrien De Mulder, Yasmine Van Caeneghem, Greet Verstichel, Nadine Van Roy, Björn Menten, Imke Velghe, Jan Philippé, Dominique De Bleser, Bart N. Lambrecht, Tom Taghon, Georges Leclercq, Tessa Kerre, Bart Vandekerckhove
    Haematologica February 2015 100: 157-166; doi:10.3324/haematol.2014.112144
    • Vanhee et al. Supplementary Appendix
    • Disclosures and Contributions

Iron Metabolism & its Disorders

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    A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis
    Patrick Gutschow, Paul J. Schmidt, Huiling Han, Vaughn Ostland, Thomas B. Bartnikas, Michael A. Pettiglio, Carolina Herrera, James S. Butler, Elizabeta Nemeth, Tomas Ganz, Mark D. Fleming, Mark Westerman
    Haematologica February 2015 100: 167-177; doi:10.3324/haematol.2014.116723
    • Gutschow et al. Supplementary Appendix
    • Disclosures and Contributions

Red Cell Biology & its Disorders

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    Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion
    Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Francesca Masiello, Giulia Federici, Maria Zingariello, Gabriella Girelli, Carolyn Whitsett, Emanuel F. Petricoin, Søren Kragh Moestrup, Ann Zeuner, Anna Rita Migliaccio
    Haematologica February 2015 100: 178-187; doi:10.3324/haematol.2014.114405
    • Falchi et al. Supplementary Appendix
    • Disclosures and Contributions

Coagulation & its Disorders

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    Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism
    Tom van der Hulle, Melanie Tan, Paul L. den Exter, Mark J.G. van Roosmalen, Felix J.M. van der Meer, Jeroen Eikenboom, Menno V. Huisman, Frederikus A. Klok
    Haematologica February 2015 100: 188-193; doi:10.3324/haematol.2014.112896
    • Disclosures and Contributions

Myelodysplastic Syndromes

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    Down-regulation of Dicer1 promotes cellular senescence and decreases the differentiation and stem cell-supporting capacities of mesenchymal stromal cells in patients with myelodysplastic syndrome
    Youshan Zhao, Dong Wu, Chengming Fei, Juan Guo, Shuncheng Gu, Yang Zhu, Feng Xu, Zheng Zhang, Lingyun Wu, Xiao Li, Chunkang Chang
    Haematologica February 2015 100: 194-204; doi:10.3324/haematol.2014.109769
    • Zhao et al. Supplementary Appendix
    • Disclosures and Contributions
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    Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group
    Friederike Braulke, Uwe Platzbecker, Catharina Müller-Thomas, Katharina Götze, Ulrich Germing, Tim H. Brümmendorf, Florian Nolte, Wolf-Karsten Hofmann, Aristoteles A. N. Giagounidis, Michael Lübbert, Peter L. Greenberg, John M. Bennett, Francesc Solé, Mar Mallo, Marilyn L. Slovak, Kazuma Ohyashiki, Michelle M. Le Beau, Heinz Tüchler, Michael Pfeilstöcker, Thomas Nösslinger, Barbara Hildebrandt, Katayoon Shirneshan, Carlo Aul, Reinhard Stauder, Wolfgang R. Sperr, Peter Valent, Christa Fonatsch, Lorenz Trümper, Detlef Haase, Julie Schanz
    Haematologica February 2015 100: 205-213; doi:10.3324/haematol.2014.110452
    • Braulke et al. Graphical Abstract
    • Braulke et al. Supplementary Appendix
    • Disclosures and Contributions

Acute Myeloid Leukemia

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    Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol
    Niccolò Bolli, Nicla Manes, Thomas McKerrell, Jianxiang Chi, Naomi Park, Gunes Gundem, Michael A. Quail, Vijitha Sathiaseelan, Bram Herman, Charles Crawley, Jenny I. O. Craig, Natalie Conte, Carolyn Grove, Elli Papaemmanuil, Peter J. Campbell, Ignacio Varela, Paul Costeas, George S. Vassiliou
    Haematologica February 2015 100: 214-222; doi:10.3324/haematol.2014.113381
    • Bolli et al. Graphical Abstract
    • Bolli et al. Supplementary Appendix
    • Disclosures and Contributions
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    In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent
    Fanny Angelot-Delettre, Anne Roggy, Arthur E. Frankel, Baptiste Lamarthee, Estelle Seilles, Sabeha Biichle, Bernard Royer, Eric Deconinck, Eric K. Rowinsky, Christopher Brooks, Valerie Bardet, Blandine Benet, Hind Bennani, Zehaira Benseddik, Agathe Debliquis, Daniel Lusina, Mikael Roussel, Françoise Solly, Michel Ticchioni, Philippe Saas, Francine Garnache-Ottou
    Haematologica February 2015 100: 223-230; doi:10.3324/haematol.2014.111740
    • Angelot-Delettre et al. Graphical Abstract
    • Angelot-Delettre et al. Supplementary Appendix
    • Disclosures and Contributions
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    A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia
    Jeffrey E. Lancet, Gail J. Roboz, Larry D. Cripe, Glenn C. Michelson, Judith A. Fox, Richard D. Leavitt, Tianling Chen, Rachael Hawtin, Adam R. Craig, Farhad Ravandi, Michael B. Maris, Robert K. Stuart, Judith E. Karp
    Haematologica February 2015 100: 231-237; doi:10.3324/haematol.2014.114769
    • Lancet et al. Supplementary Appendix
    • Disclosures and Contributions

Non-Hodgkin Lymphoma

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    Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial
    Sari Riihijärvi, Idun Fiskvik, Minna Taskinen, Heli Vajavaara, Maria Tikkala, Olav Yri, Marja-Liisa Karjalainen-Lindsberg, Jan Delabie, Erlend Smeland, Harald Holte, Sirpa Leppä
    Haematologica February 2015 100: 238-245; doi:10.3324/haematol.2014.113472
    • Riihijarvi et al. Graphical Abstract
    • Riihijarvi et al. Supplementary Appendix
    • Disclosures and Contributions
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    The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection
    Luca Arcaini, Davide Rossi, Marco Lucioni, Marta Nicola, Alessio Bruscaggin, Valeria Fiaccadori, Roberta Riboni, Antonio Ramponi, Virginia V. Ferretti, Stefania Cresta, Gloria Margiotta Casaluci, Maurizio Bonfichi, Manuel Gotti, Michele Merli, Aldo Maffi, Mariarosa Arra, Marzia Varettoni, Sara Rattotti, Lucia Morello, Maria Luisa Guerrera, Roberta Sciarra, Gianluca Gaidano, Mario Cazzola, Marco Paulli
    Haematologica February 2015 100: 246-252; doi:10.3324/haematol.2014.116855
    • Arcaini et al. Supplementary Appendix
    • Disclosures and Contributions

Chronic Lymphocytic Leukemia

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    Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia
    Stefania Fiorcari, Silvia Martinelli, Jenny Bulgarelli, Valentina Audrito, Patrizia Zucchini, Elisabetta Colaci, Leonardo Potenza, Franco Narni, Mario Luppi, Silvia Deaglio, Roberto Marasca, Rossana Maffei
    Haematologica February 2015 100: 253-262; doi:10.3324/haematol.2014.113217
    • Fiorcari et al. Supplementary Appendix
    • Disclosures and Contributions

Plasma Cell Disorders

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    Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide
    Inger S. Nijhof, Jeroen J. Lammerts van Bueren, Berris van Kessel, Pascale Andre, Yannis Morel, Henk M. Lokhorst, Niels W.C.J. van de Donk, Paul W.H.I. Parren, Tuna Mutis
    Haematologica February 2015 100: 263-268; doi:10.3324/haematol.2014.117531
    • Disclosures and Contributions

Stem Cell Transplantation

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    Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial
    Didier Blaise, Raynier Devillier, Anne-Gaëlle Lecoroller-Sorriano, Jean-Marie Boher, Agnès Boyer-Chammard, Reza Tabrizi, Patrice Chevallier, Nathalie Fegueux, Anne Sirvent, Mauricette Michallet, Jacques-Olivier Bay, Sabine Fürst, Jean El-Cheikh, Laure Vincent, Thierry Guillaume, Caroline Regny, Noël Milpied, Luca Castagna, Mohamad Mohty
    Haematologica February 2015 100: 269-274; doi:10.3324/haematol.2014.113571
    • Blaise et al. Supplementary Appendix
    • Disclosures and Contributions
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    Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease
    Isabelle Laverdière, Chantal Guillemette, Ryad Tamouza, Pascale Loiseau, Regis Peffault de Latour, Marie Robin, Félix Couture, Alain Filion, Marc Lalancette, Alan Tourancheau, Dominique Charron, Gérard Socié, Éric Lévesque
    Haematologica February 2015 100: 275-283; doi:10.3324/haematol.2014.109884
    • Laverdiere et al. Supplementary Appendix
    • Disclosures and Contributions

Complications in Hematology

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    Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM 2010-a multicenter study)
    Morena Caira, Anna Candoni, Luisa Verga, Alessandro Busca, Mario Delia, Annamaria Nosari, Cecilia Caramatti, Carlo Castagnola, Chiara Cattaneo, Rosa Fanci, Anna Chierichini, Lorella Melillo, Maria Enza Mitra, Marco Picardi, Leonardo Potenza, Prassede Salutari, Nicola Vianelli, Luca Facchini, Monica Cesarini, Maria Rosaria De Paolis, Roberta Di Blasi, Francesca Farina, Adriano Venditti, Antonella Ferrari, Mariagrazia Garzia, Cristina Gasbarrino, Rosangela Invernizzi, Federica Lessi, Annunziata Manna, Bruno Martino, Gianpaolo Nadali, Massimo Offidani, Laura Paris, Vincenzo Pavone, Giuseppe Rossi, Antonio Spadea, Giorgina Specchia, Enrico Maria Trecarichi, Adriana Vacca, Simone Cesaro, Vincenzo Perriello, Franco Aversa, Mario Tumbarello, Livio Pagano
    Haematologica February 2015 100: 284-292; doi:10.3324/haematol.2014.113399
    • Caira et al. Graphical Abstract
    • Disclosures and Contributions

Letters to the Editor

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    IL-1β-releasing human acute myeloid leukemia blasts modulate natural killer cell differentiation from CD34+ precursors
    Chiara Vitale, Paolo Ambrosini, Elisa Montaldo, Filippo Ballerini, Lorenzo Moretta, Maria Cristina Mingari
    Haematologica February 2015 100: e42-e45; doi:10.3324/haematol.2014.110494
    • Disclosures and Contributions
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    JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms
    Shuichi Shirane, Marito Araki, Soji Morishita, Yoko Edahiro, Hiraku Takei, Yongjin Yoo, Murim Choi, Yoshitaka Sunami, Yumi Hironaka, Masaaki Noguchi, Michiaki Koike, Naohiro Noda, Akimichi Ohsaka, Norio Komatsu
    Haematologica February 2015 100: e46-e48; doi:10.3324/haematol.2014.115113
    • Shirane et al. Supplementary Appendix
    • Disclosures and Contributions
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    Pharmacological targeting of β-catenin in normal karyotype acute myeloid leukemia blasts
    Elizabeth A. Griffiths, Michelle C. Golding, Pragya Srivastava, Benjamin J. Povinelli, Smitha R. James, Laurie A. Ford, Meir Wetzler, Eunice S. Wang, Michael J. Nemeth
    Haematologica February 2015 100: e49-e52; doi:10.3324/haematol.2014.113118
    • Disclosures and Contributions
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    The prognostic value of multiparameter flow cytometry minimal residual disease assessment in relapsed multiple myeloma
    Bruno Paiva, Mauricio Chandia, Noemi Puig, Maria-Belen Vidriales, Jose J. Perez, Lucia Lopez-Corral, Enrique M. Ocio, Ramon Garcia-Sanz, Norma C. Gutierrez, Ana Jimenez-Ubieto, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San Miguel
    Haematologica February 2015 100: e53-e55; doi:10.3324/haematol.2014.115162
    • Disclosures and Contributions
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    Phase II study of bendamustine, bortezomib and dexamethasone as second-line treatment for elderly patients with multiple myeloma: the Intergroupe Francophone du Myelome 2009-01 trial
    Philippe Rodon, Cyrille Hulin, Brigitte Pegourie, Mourad Tiab, Bruno Anglaret, Lotfi Benboubker, Henry Jardel, Olivier Decaux, Brigitte Kolb, Murielle Roussel, Laurent Garderet, Xavier Leleu, Olivier Fitoussi, Carine Chaleteix, Philippe Casassus, Pascal Lenain, Bruno Royer, Anne Banos, Riad Benramdane, Pascale Cony-Makhoul, Mamoun Dib, Jean Fontan, Anne-Marie Stoppa, Catherine Traullé, Jean-Pierre Vilque, Marie-Odile Pétillon, Claire Mathiot, Thomas Dejoie, Hervé Avet-Loiseau, Philippe Moreau
    Haematologica February 2015 100: e56-e59; doi:10.3324/haematol.2014.110890
    • Disclosures and Contributions
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    A rare case of IGH/MYC and IGH/BCL2 double hit primary plasma cell leukemia
    Anna Kalff, Tiffany Khong, Meaghan Wall, Malgorzata Gorniak, Sridurga Mithraprabhu, Lynda J. Campbell, Andrew Spencer
    Haematologica February 2015 100: e60-e62; doi:10.3324/haematol.2014.111385
    • Disclosures and Contributions
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    Health-related quality of life from the MM-003 trial of pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed and/or refractory multiple myeloma
    Kevin W. Song, Meletios A. Dimopoulos, Katja C. Weisel, Philippe Moreau, Antonio Palumbo, Andrew Belch, Stephen Schey, Pieter Sonneveld, Lars Sternas, Xin Yu, Ramesh Amatya, Mara S. Monzini, Mohamed Zaki, Christian Jacques, Jesus San Miguel
    Haematologica February 2015 100: e63-e67; doi:10.3324/haematol.2014.112557
    • Disclosures and Contributions
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    Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation
    Claire Mayeur, Starsha A. Kolodziej, Amy Wang, Xin Xu, Arthur Lee, Paul B. Yu, John Shen, Kenneth D. Bloch, Donald B. Bloch
    Haematologica February 2015 100: e68-e71; doi:10.3324/haematol.2014.111484
    • Mayeur et al. Supplementary Appendix
    • Disclosures and Contributions
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    Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency
    Polina Stepensky, Baerbel Keller, Omar Abuzaitoun, Avraham Shaag, Barak Yaacov, Susanne Unger, Maximilian Seidl, Marta Rizzi, Michael Weintraub, Orly Elpeleg, Klaus Warnatz
    Haematologica February 2015 100: e72-e76; doi:10.3324/haematol.2014.112508
    • Stepensky et al. Supplementary Appendix
    • Disclosures and Contributions
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Haematologica: 100 (2)
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