Haematologica: 100 (2)

January 31, 2015 ; 100 (2)

Editorials

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Tumor-associated macrophages in diffuse large B-cell lymphoma
Robert Kridel, Christian Steidl, Randy D. Gascoyne

Haematologica February 2015 100: 143-145; doi:10.3324/haematol.2015.124008
Disclosures
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Inherited thrombocytopenias in the era of personalized medicine
Patrizia Noris, Carlo L. Balduini

Haematologica February 2015 100: 145-148; doi:10.3324/haematol.2014.122549
Disclosures

Review Article

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Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicity
Johannes Oldenburg, Sébastien Lacroix-Desmazes, David Lillicrap

Haematologica February 2015 100: 149-156; doi:10.3324/haematol.2014.112821
Disclosures and Contributions

Articles

Hematopoiesis

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In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis
Stijn Vanhee, Katrien De Mulder, Yasmine Van Caeneghem, Greet Verstichel, Nadine Van Roy, Björn Menten, Imke Velghe, Jan Philippé, Dominique De Bleser, Bart N. Lambrecht, Tom Taghon, Georges Leclercq, Tessa Kerre, Bart Vandekerckhove

Haematologica February 2015 100: 157-166; doi:10.3324/haematol.2014.112144
Vanhee et al. Supplementary Appendix
Disclosures and Contributions

Iron Metabolism & its Disorders

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A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis
Patrick Gutschow, Paul J. Schmidt, Huiling Han, Vaughn Ostland, Thomas B. Bartnikas, Michael A. Pettiglio, Carolina Herrera, James S. Butler, Elizabeta Nemeth, Tomas Ganz, Mark D. Fleming, Mark Westerman

Haematologica February 2015 100: 167-177; doi:10.3324/haematol.2014.116723
Gutschow et al. Supplementary Appendix
Disclosures and Contributions

Red Cell Biology & its Disorders

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Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion
Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Francesca Masiello, Giulia Federici, Maria Zingariello, Gabriella Girelli, Carolyn Whitsett, Emanuel F. Petricoin, Søren Kragh Moestrup, Ann Zeuner, Anna Rita Migliaccio

Haematologica February 2015 100: 178-187; doi:10.3324/haematol.2014.114405
Falchi et al. Supplementary Appendix
Disclosures and Contributions

Coagulation & its Disorders

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Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism
Tom van der Hulle, Melanie Tan, Paul L. den Exter, Mark J.G. van Roosmalen, Felix J.M. van der Meer, Jeroen Eikenboom, Menno V. Huisman, Frederikus A. Klok

Haematologica February 2015 100: 188-193; doi:10.3324/haematol.2014.112896
Disclosures and Contributions

Myelodysplastic Syndromes

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Down-regulation of Dicer1 promotes cellular senescence and decreases the differentiation and stem cell-supporting capacities of mesenchymal stromal cells in patients with myelodysplastic syndrome
Youshan Zhao, Dong Wu, Chengming Fei, Juan Guo, Shuncheng Gu, Yang Zhu, Feng Xu, Zheng Zhang, Lingyun Wu, Xiao Li, Chunkang Chang

Haematologica February 2015 100: 194-204; doi:10.3324/haematol.2014.109769
Zhao et al. Supplementary Appendix
Disclosures and Contributions
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Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34⁺FISH: results from a German diagnostic study in comparison with an international control group
Friederike Braulke, Uwe Platzbecker, Catharina Müller-Thomas, Katharina Götze, Ulrich Germing, Tim H. Brümmendorf, Florian Nolte, Wolf-Karsten Hofmann, Aristoteles A. N. Giagounidis, Michael Lübbert, Peter L. Greenberg, John M. Bennett, Francesc Solé, Mar Mallo, Marilyn L. Slovak, Kazuma Ohyashiki, Michelle M. Le Beau, Heinz Tüchler, Michael Pfeilstöcker, Thomas Nösslinger, Barbara Hildebrandt, Katayoon Shirneshan, Carlo Aul, Reinhard Stauder, Wolfgang R. Sperr, Peter Valent, Christa Fonatsch, Lorenz Trümper, Detlef Haase, Julie Schanz

Haematologica February 2015 100: 205-213; doi:10.3324/haematol.2014.110452
Braulke et al. Graphical Abstract
Braulke et al. Supplementary Appendix
Disclosures and Contributions

Acute Myeloid Leukemia

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Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol
Niccolò Bolli, Nicla Manes, Thomas McKerrell, Jianxiang Chi, Naomi Park, Gunes Gundem, Michael A. Quail, Vijitha Sathiaseelan, Bram Herman, Charles Crawley, Jenny I. O. Craig, Natalie Conte, Carolyn Grove, Elli Papaemmanuil, Peter J. Campbell, Ignacio Varela, Paul Costeas, George S. Vassiliou

Haematologica February 2015 100: 214-222; doi:10.3324/haematol.2014.113381
Bolli et al. Graphical Abstract
Bolli et al. Supplementary Appendix
Disclosures and Contributions
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In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent
Fanny Angelot-Delettre, Anne Roggy, Arthur E. Frankel, Baptiste Lamarthee, Estelle Seilles, Sabeha Biichle, Bernard Royer, Eric Deconinck, Eric K. Rowinsky, Christopher Brooks, Valerie Bardet, Blandine Benet, Hind Bennani, Zehaira Benseddik, Agathe Debliquis, Daniel Lusina, Mikael Roussel, Françoise Solly, Michel Ticchioni, Philippe Saas, Francine Garnache-Ottou

Haematologica February 2015 100: 223-230; doi:10.3324/haematol.2014.111740
Angelot-Delettre et al. Graphical Abstract
Angelot-Delettre et al. Supplementary Appendix
Disclosures and Contributions
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A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia
Jeffrey E. Lancet, Gail J. Roboz, Larry D. Cripe, Glenn C. Michelson, Judith A. Fox, Richard D. Leavitt, Tianling Chen, Rachael Hawtin, Adam R. Craig, Farhad Ravandi, Michael B. Maris, Robert K. Stuart, Judith E. Karp

Haematologica February 2015 100: 231-237; doi:10.3324/haematol.2014.114769
Lancet et al. Supplementary Appendix
Disclosures and Contributions

Non-Hodgkin Lymphoma

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Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial
Sari Riihijärvi, Idun Fiskvik, Minna Taskinen, Heli Vajavaara, Maria Tikkala, Olav Yri, Marja-Liisa Karjalainen-Lindsberg, Jan Delabie, Erlend Smeland, Harald Holte, Sirpa Leppä

Haematologica February 2015 100: 238-245; doi:10.3324/haematol.2014.113472
Riihijarvi et al. Graphical Abstract
Riihijarvi et al. Supplementary Appendix
Disclosures and Contributions
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The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection
Luca Arcaini, Davide Rossi, Marco Lucioni, Marta Nicola, Alessio Bruscaggin, Valeria Fiaccadori, Roberta Riboni, Antonio Ramponi, Virginia V. Ferretti, Stefania Cresta, Gloria Margiotta Casaluci, Maurizio Bonfichi, Manuel Gotti, Michele Merli, Aldo Maffi, Mariarosa Arra, Marzia Varettoni, Sara Rattotti, Lucia Morello, Maria Luisa Guerrera, Roberta Sciarra, Gianluca Gaidano, Mario Cazzola, Marco Paulli

Haematologica February 2015 100: 246-252; doi:10.3324/haematol.2014.116855
Arcaini et al. Supplementary Appendix
Disclosures and Contributions

Chronic Lymphocytic Leukemia

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Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia
Stefania Fiorcari, Silvia Martinelli, Jenny Bulgarelli, Valentina Audrito, Patrizia Zucchini, Elisabetta Colaci, Leonardo Potenza, Franco Narni, Mario Luppi, Silvia Deaglio, Roberto Marasca, Rossana Maffei

Haematologica February 2015 100: 253-262; doi:10.3324/haematol.2014.113217
Fiorcari et al. Supplementary Appendix
Disclosures and Contributions

Plasma Cell Disorders

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Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide
Inger S. Nijhof, Jeroen J. Lammerts van Bueren, Berris van Kessel, Pascale Andre, Yannis Morel, Henk M. Lokhorst, Niels W.C.J. van de Donk, Paul W.H.I. Parren, Tuna Mutis

Haematologica February 2015 100: 263-268; doi:10.3324/haematol.2014.117531
Disclosures and Contributions

Stem Cell Transplantation

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Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial
Didier Blaise, Raynier Devillier, Anne-Gaëlle Lecoroller-Sorriano, Jean-Marie Boher, Agnès Boyer-Chammard, Reza Tabrizi, Patrice Chevallier, Nathalie Fegueux, Anne Sirvent, Mauricette Michallet, Jacques-Olivier Bay, Sabine Fürst, Jean El-Cheikh, Laure Vincent, Thierry Guillaume, Caroline Regny, Noël Milpied, Luca Castagna, Mohamad Mohty

Haematologica February 2015 100: 269-274; doi:10.3324/haematol.2014.113571
Blaise et al. Supplementary Appendix
Disclosures and Contributions
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Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease
Isabelle Laverdière, Chantal Guillemette, Ryad Tamouza, Pascale Loiseau, Regis Peffault de Latour, Marie Robin, Félix Couture, Alain Filion, Marc Lalancette, Alan Tourancheau, Dominique Charron, Gérard Socié, Éric Lévesque

Haematologica February 2015 100: 275-283; doi:10.3324/haematol.2014.109884
Laverdiere et al. Supplementary Appendix
Disclosures and Contributions

Complications in Hematology

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Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM 2010-a multicenter study)
Morena Caira, Anna Candoni, Luisa Verga, Alessandro Busca, Mario Delia, Annamaria Nosari, Cecilia Caramatti, Carlo Castagnola, Chiara Cattaneo, Rosa Fanci, Anna Chierichini, Lorella Melillo, Maria Enza Mitra, Marco Picardi, Leonardo Potenza, Prassede Salutari, Nicola Vianelli, Luca Facchini, Monica Cesarini, Maria Rosaria De Paolis, Roberta Di Blasi, Francesca Farina, Adriano Venditti, Antonella Ferrari, Mariagrazia Garzia, Cristina Gasbarrino, Rosangela Invernizzi, Federica Lessi, Annunziata Manna, Bruno Martino, Gianpaolo Nadali, Massimo Offidani, Laura Paris, Vincenzo Pavone, Giuseppe Rossi, Antonio Spadea, Giorgina Specchia, Enrico Maria Trecarichi, Adriana Vacca, Simone Cesaro, Vincenzo Perriello, Franco Aversa, Mario Tumbarello, Livio Pagano

Haematologica February 2015 100: 284-292; doi:10.3324/haematol.2014.113399
Caira et al. Graphical Abstract
Disclosures and Contributions

Letters to the Editor

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IL-1β-releasing human acute myeloid leukemia blasts modulate natural killer cell differentiation from CD34⁺ precursors
Chiara Vitale, Paolo Ambrosini, Elisa Montaldo, Filippo Ballerini, Lorenzo Moretta, Maria Cristina Mingari

Haematologica February 2015 100: e42-e45; doi:10.3324/haematol.2014.110494
Disclosures and Contributions
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JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms
Shuichi Shirane, Marito Araki, Soji Morishita, Yoko Edahiro, Hiraku Takei, Yongjin Yoo, Murim Choi, Yoshitaka Sunami, Yumi Hironaka, Masaaki Noguchi, Michiaki Koike, Naohiro Noda, Akimichi Ohsaka, Norio Komatsu

Haematologica February 2015 100: e46-e48; doi:10.3324/haematol.2014.115113
Shirane et al. Supplementary Appendix
Disclosures and Contributions
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Pharmacological targeting of β-catenin in normal karyotype acute myeloid leukemia blasts
Elizabeth A. Griffiths, Michelle C. Golding, Pragya Srivastava, Benjamin J. Povinelli, Smitha R. James, Laurie A. Ford, Meir Wetzler, Eunice S. Wang, Michael J. Nemeth

Haematologica February 2015 100: e49-e52; doi:10.3324/haematol.2014.113118
Disclosures and Contributions
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The prognostic value of multiparameter flow cytometry minimal residual disease assessment in relapsed multiple myeloma
Bruno Paiva, Mauricio Chandia, Noemi Puig, Maria-Belen Vidriales, Jose J. Perez, Lucia Lopez-Corral, Enrique M. Ocio, Ramon Garcia-Sanz, Norma C. Gutierrez, Ana Jimenez-Ubieto, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San Miguel

Haematologica February 2015 100: e53-e55; doi:10.3324/haematol.2014.115162
Disclosures and Contributions
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Phase II study of bendamustine, bortezomib and dexamethasone as second-line treatment for elderly patients with multiple myeloma: the Intergroupe Francophone du Myelome 2009-01 trial
Philippe Rodon, Cyrille Hulin, Brigitte Pegourie, Mourad Tiab, Bruno Anglaret, Lotfi Benboubker, Henry Jardel, Olivier Decaux, Brigitte Kolb, Murielle Roussel, Laurent Garderet, Xavier Leleu, Olivier Fitoussi, Carine Chaleteix, Philippe Casassus, Pascal Lenain, Bruno Royer, Anne Banos, Riad Benramdane, Pascale Cony-Makhoul, Mamoun Dib, Jean Fontan, Anne-Marie Stoppa, Catherine Traullé, Jean-Pierre Vilque, Marie-Odile Pétillon, Claire Mathiot, Thomas Dejoie, Hervé Avet-Loiseau, Philippe Moreau

Haematologica February 2015 100: e56-e59; doi:10.3324/haematol.2014.110890
Disclosures and Contributions
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A rare case of IGH/MYC and IGH/BCL2 double hit primary plasma cell leukemia
Anna Kalff, Tiffany Khong, Meaghan Wall, Malgorzata Gorniak, Sridurga Mithraprabhu, Lynda J. Campbell, Andrew Spencer

Haematologica February 2015 100: e60-e62; doi:10.3324/haematol.2014.111385
Disclosures and Contributions
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Health-related quality of life from the MM-003 trial of pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed and/or refractory multiple myeloma
Kevin W. Song, Meletios A. Dimopoulos, Katja C. Weisel, Philippe Moreau, Antonio Palumbo, Andrew Belch, Stephen Schey, Pieter Sonneveld, Lars Sternas, Xin Yu, Ramesh Amatya, Mara S. Monzini, Mohamed Zaki, Christian Jacques, Jesus San Miguel

Haematologica February 2015 100: e63-e67; doi:10.3324/haematol.2014.112557
Disclosures and Contributions
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Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation
Claire Mayeur, Starsha A. Kolodziej, Amy Wang, Xin Xu, Arthur Lee, Paul B. Yu, John Shen, Kenneth D. Bloch, Donald B. Bloch

Haematologica February 2015 100: e68-e71; doi:10.3324/haematol.2014.111484
Mayeur et al. Supplementary Appendix
Disclosures and Contributions
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Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency
Polina Stepensky, Baerbel Keller, Omar Abuzaitoun, Avraham Shaag, Barak Yaacov, Susanne Unger, Maximilian Seidl, Marta Rizzi, Michael Weintraub, Orly Elpeleg, Klaus Warnatz

Haematologica February 2015 100: e72-e76; doi:10.3324/haematol.2014.112508
Stepensky et al. Supplementary Appendix
Disclosures and Contributions

Table of Contents

Editorials

Review Article

Articles

Hematopoiesis

Iron Metabolism & its Disorders

Red Cell Biology & its Disorders

Coagulation & its Disorders

Myelodysplastic Syndromes

Acute Myeloid Leukemia

Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia

Plasma Cell Disorders

Stem Cell Transplantation

Complications in Hematology

Letters to the Editor

In this issue

Table of Contents

Editorials

Review Article

Articles

Hematopoiesis

Iron Metabolism & its Disorders

Red Cell Biology & its Disorders

Coagulation & its Disorders

Myelodysplastic Syndromes

Acute Myeloid Leukemia

Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia

Plasma Cell Disorders

Stem Cell Transplantation

Complications in Hematology

Letters to the Editor

In this issue

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