Table of Contents

Articles

• Red Cell Biology & Its Disorders

  • Open Access

    Clinical risks and healthcare utilization of hematopoietic cell transplantation for sickle cell disease in the USA using merged databases

    Staci D. Arnold, Ruta Brazauskas, Naya He, Yimei Li, Richard Aplenc, Zhezhen Jin, Matt Hall, Yoshiko Atsuta, Jignesh Dalal, Theresa Hahn, Nandita Khera, Carmem Bonfim, Navneet S. Majhail, Miguel Angel Diaz, Cesar O. Freytes, William A. Wood, Bipin N. Savani, Rammurti T. Kamble, Susan Parsons, Ibrahim Ahmed, Keith Sullivan, Sara Beattie, Christopher Dandoy, Reinhold Munker, Susana Marino, Menachem Bitan, Hisham Abdel-Azim, Mahmoud Aljurf, Richard F. Olsson, Sarita Joshi, Dave Buchbinder, Michael J. Eckrich, Shahrukh Hashmi, Hillard Lazarus, David I. Marks, Amir Steinberg, Ayman Saad, Usama Gergis, Lakshmanan Krishnamurti, Allistair Abraham, Hemalatha G. Rangarajan, Mark Walters, Joseph Lipscomb, Wael Saber, Prakash Satwani

    Haematologica November 2017 102: 1823-1832; doi:10.3324/haematol.2017.169581

    • Arnold et al. Supplementary Appendix
    • Disclosures and Contributions

• Coagulation & Its Disorders

  • Open Access

    The ADAMTS13^1239–1253 peptide is a dominant HLA-DR1-restricted CD4⁺ T-cell epitope

    Laurent Gilardin, Sandrine Delignat, Ivan Peyron, Mathieu Ing, Yu-Chun Lone, Bagirath Gangadharan, Baptiste Michard, Yousra Kherabi, Meenu Sharma, Anastas Pashov, Jean-Baptiste Latouche, Mohamad Hamieh, Olivier Toutirais, Pascale Loiseau, Lionel Galicier, Agnès Veyradier, Srini Kaveri, Bernard Maillère, Paul Coppo, Sébastien Lacroix-Desmazes

    Haematologica November 2017 102: 1833-1841; doi:10.3324/haematol.2015.136671

    • Disclosures and Contributions

• Chronic Myeloid Leukemia

  • Open Access

    Treatment outcome in a population-based, ‘real-world’ cohort of patients with chronic myeloid leukemia

    Inge G.P. Geelen, Noortje Thielen, Jeroen J.W.M. Janssen, Mels Hoogendoorn, Tanja J.A. Roosma, Sten P. Willemsen, Otto Visser, Jan J. Cornelissen, Peter E. Westerweel

    Haematologica November 2017 102: 1842-1849; doi:10.3324/haematol.2017.174953

    • Geelen et al. Graphical Abstract
    • Geelen et al. Supplementary Appendix
    • Disclosures and Contributions

• Acute Myeloid Leukemia

  • Open Access

    Senescence is a Spi1-induced anti-proliferative mechanism in primary hematopoietic cells

    Laure Delestré, Hengxiang Cui, Michela Esposito, Cyril Quiveron, Elena Mylonas, Virginie Penard-Lacronique, Oliver Bischof, Christel Guillouf

    Haematologica November 2017 102: 1850-1860; doi:10.3324/haematol.2016.157636

    • Delestre et al. Graphical Abstract
    • Disclosures and Contributions
    • Delestre et al. Supplementary Appendix
  • Open Access

    Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm

    Laure Philippe, Adam Ceroi, Elodie Bôle-Richard, Alizée Jenvrin, Sabeha Biichle, Sophie Perrin, Samuel Limat, Francis Bonnefoy, Eric Deconinck, Philippe Saas, Francine Garnache-Ottou, Fanny Angelot-Delettre

    Haematologica November 2017 102: 1861-1868; doi:10.3324/haematol.2017.169326

    • Philippe et al. Supplementary Appendix
    • Disclosures and Contributions

• Acute Lymphoblastic Leukemia

  • Open Access

    Antigen receptor sequencing of paired bone marrow samples shows homogeneous distribution of acute lymphoblastic leukemia subclones

    Prisca M.J. Theunissen, David van Zessen, Andrew P. Stubbs, Malek Faham, Christian M. Zwaan, Jacques J.M. van Dongen, Vincent H.J. Van Der Velden

    Haematologica November 2017 102: 1869-1877; doi:10.3324/haematol.2017.171454

    • Theunissen et al. Supplementary Appendix
    • Disclosures and Contributions

• Chronic Lymphocytic Leukemia

  • Open Access

    Targeting metabolism and survival in chronic lymphocytic leukemia and Richter syndrome cells by a novel NF-κB inhibitor

    Tiziana Vaisitti, Federica Gaudino, Samedy Ouk, Maria Moscvin, Nicoletta Vitale, Sara Serra, Francesca Arruga, Johannes L. Zakrzewski, Hsiou-Chi Liou, John N. Allan, Richard R. Furman, Silvia Deaglio

    Haematologica November 2017 102: 1878-1889; doi:10.3324/haematol.2017.173419

    • Vaisitti et al. Graphical Abstract
    • Vaisitti et al. Supplementary Appendix
    • Disclosures and Contributions
  • Open Access

    SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia

    Cody Paiva, Taylor A. Rowland, Bhargava Sreekantham, Claire Godbersen, Scott R. Best, Prabhjot Kaur, Marc M. Loriaux, Stephen E.F. Spurgeon, Olga V. Danilova, Alexey V. Danilov

    Haematologica November 2017 102: 1890-1900; doi:10.3324/haematol.2017.170571

    • Paiva et al. Supplementary Appendix
    • Disclosures and Contributions
  • Open Access

    Toll-like receptor 9 stimulation can induce IκBζ expression and IgM secretion in chronic lymphocytic leukemia cells

    Eleonora Fonte, Maria Giovanna Vilia, Daniele Reverberi, Ilenia Sana, Lydia Scarfò, Pamela Ranghetti, Ugo Orfanelli, Simone Cenci, Giovanna Cutrona, Paolo Ghia, Marta Muzio

    Haematologica November 2017 102: 1901-1912; doi:10.3324/haematol.2017.165878

    • Fonte et al. Supplementary Appendix
    • Disclosures and Contributions

• Non-Hodgkin Lymphoma

  • Open Access

    Efficacy and safety of subcutaneous and intravenous rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in first-line diffuse large B-cell lymphoma: the randomized MabEase study

    Pieternella Lugtenburg, Irit Avivi, Henriette Berenschot, Osman Ilhan, Jean Pierre Marolleau, Arnon Nagler, Antonio Rueda, Monica Tani, Mehmet Turgut, Stuart Osborne, Rodney Smith, Michael Pfreundschuh

    Haematologica November 2017 102: 1913-1922; doi:10.3324/haematol.2017.173583

    • Lugtenburg et al. Supplementary Appendix
    • Disclosures and Contributions
  • Open Access

    CUDC-907 in relapsed/refractory diffuse large B-cell lymphoma, including patients with MYC-alterations: results from an expanded phase I trial

    Yasuhiro Oki, Kevin R Kelly, Ian Flinn, Manish R. Patel, Robert Gharavi, Anna Ma, Jefferson Parker, Amir Hafeez, David Tuck, Anas Younes

    Haematologica November 2017 102: 1923-1930; doi:10.3324/haematol.2017.172882

    • Oki et al. Supplementary Appendix
    • Disclosures and Contributions
  • Open Access

    Italian real-life experience with brentuximab vedotin: results of a large observational study of 40 cases of relapsed/refractory systemic anaplastic large cell lymphoma

    Alessandro Broccoli, Cinzia Pellegrini, Alice Di Rocco, Benedetta Puccini, Caterina Patti, Guido Gini, Donato Mannina, Monica Tani, Chiara Rusconi, Alessandra Romano, Anna Vanazzi, Barbara Botto, Carmelo Carlo-Stella, Stefan Hohaus, Pellegrino Musto, Patrizio Mazza, Stefano Molica, Paolo Corradini, Angelo Fama, Francesco Gaudio, Michele Merli, Angela Gravetti, Giuseppe Gritti, Annalisa Arcari, Patrizia Tosi, Anna Marina Liberati, Antonello Pinto, Vincenzo Pavone, Filippo Gherlinzoni, Virginia Naso, Stefano Volpetti, Livio Trentin, Maria Cecilia Goldaniga, Maurizio Bonfichi, Amalia De Renzo, Corrado Schiavotto, Michele Spina, Sergio Storti, Angelo Michele Carella, Vittorio Stefoni, Lisa Argnani, Pier Luigi Zinzani

    Haematologica November 2017 102: 1931-1935; doi:10.3324/haematol.2017.171355

    • Broccoli et al. Graphical Abstract
    • Disclosures and Contributions

• Cell Therapy & Immunotherapy

  • Open Access

    CD56^bright natural killer regulatory cells in filgrastim primed donor blood or marrow products regulate chronic graft-versus-host disease: the Canadian Blood and Marrow Transplant Group randomized 0601 study results

    Amina Kariminia, Sabine Ivison, Bernard Ng, Jacob Rozmus, Susanna Sung, Avani Varshney, Mahmoud Aljurf, Sylvie Lachance, Irwin Walker, Cindy Toze, Jeff Lipton, Stephanie J. Lee, Jeff Szer, Richard Doocey, Ian Lewis, Clayton Smith, Naeem Chaudhri, Megan K. Levings, Raewyn Broady, Gerald Devins, David Szwajcer, Ronan Foley, Sara Mostafavi, Steven Pavletic, Donna A. Wall, Stephan Couban, Tony Panzarella, Kirk R. Schultz

    Haematologica November 2017 102: 1936-1946; doi:10.3324/haematol.2017.170928

    • Kariminia et al. Supplementary Appendix
    • Disclosures and Contributions
  • Open Access

    Human leukocyte antigen-E mismatch is associated with better hematopoietic stem cell transplantation outcome in acute leukemia patients

    Chrysanthi Tsamadou, Daniel Fürst, Vladan Vucinic, Donald Bunjes, Christine Neuchel, Daphne Mytilineos, Martin Gramatzki, Renate Arnold, Eva Maria Wagner, Hermann Einsele, Carlheinz Müller, Hubert Schrezenmeier, Joannis Mytilineos

    Haematologica November 2017 102: 1947-1955; doi:10.3324/haematol.2017.169805

    • Tsamadou et al. Graphical Abstract
    • Tsamadou et al. Supplementary Appendix
    • Disclosures and Contributions

• Complications in Hematology

  • Open Access

    HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis

    Rui Huang, Yoshihiro Hayashi, Xiaomei Yan, Jiachen Bu, Jieyu Wang, Yue Zhang, Yile Zhou, Yuting Tang, Lingyun Wu, Zefeng Xu, Xin Liu, Qianfei Wang, Jianfeng Zhou, Zhijian Xiao, James P. Bridges, Rebecca A. Marsh, Kejian Zhang, Michael B. Jordan, Yuhua Li, Gang Huang

    Haematologica November 2017 102: 1956-1968; doi:10.3324/haematol.2017.174979

    • Huang et al. Supplementary Appendix
    • Disclosures and Contributions