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Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of β-thalassemia

Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK;Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Sri Lanka
Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK
Weatherall Institute of Molecular Medicine, University of Oxford, UK
Weatherall Institute of Molecular Medicine, University of Oxford, UK
Structural Genomics Consortium, University of Oxford, UK;The Botnar Research Centre, NIHR BRU Oxford, University of Oxford, UK
Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK
Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK;Oxford National Institute for Health Research Biomedical Research Centre, Blood Theme, Oxford University Hospital, UK
Vol. 102 No. 3 (2017): March, 2017 https://doi.org/10.3324/haematol.2016.155655