Articles

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation

Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA
Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA;Division of Hematology/Oncology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Department of Surgery and Pharmaceutical Sciences, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA
Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA;Division of Hematology/Oncology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Department of Human Genetics, University of Pittsburgh Graduate School of Public Health and Cancer Institute, and the University of Pittsburgh Cell Culture and Cytogenetics Facility, PA, USA
Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA;Columbia Center for Translational Immunology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA;Columbia Center for Translational Immunology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Department of Cell Biology and Physiology, University of Pittsburgh, PA, USA
Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA;Division of Hematology/Oncology, College of Physicians and Surgeons, Columbia University, New York, NY, USA;Columbia Center for Translational Immunology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine and Cancer Institute, PA, USA;Division of Hematology/Oncology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Vol. 103 No. 10 (2018): October, 2018 https://doi.org/10.3324/haematol.2018.188227