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IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma

Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Würzburg, Germany
Department of Hematology, Mayo Clinic, Scottsdale, AZ, USA
Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany and CCU Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Germany
Department of Hematology, Mayo Clinic, Scottsdale, AZ, USA
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Hematology Department Hospital 12 de Octubre, Complutense University, H12O-CNIO Clinical Research Unit, CIBERONC Madrid, Spain
Department of Hematology, Mayo Clinic, Scottsdale, AZ, USA
Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Hematology Department Hospital 12 de Octubre, Complutense University, H12O-CNIO Clinical Research Unit, CIBERONC Madrid, Spain
Gene Center, Ludwig-Maximilians University, Munich, Germany
Department of Hematology, Mayo Clinic, Scottsdale, AZ, USA
Institute of Pathology, University of Würzburg, Würzburg, Germany
Hematology Department Hospital 12 de Octubre, Complutense University, H12O-CNIO Clinical Research Unit, CIBERONC Madrid, Spain
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany and CCU Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Germany
Department of Hematology, Mayo Clinic, Scottsdale, AZ, USA;Center for Individualized Medicine of the Mayo Clinic, Rochester, MN, USA
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Würzburg, Germany
Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany
Vol. 105 No. 5 (2020): May, 2020 https://doi.org/10.3324/haematol.2019.217943