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Linkage analysis combined with whole-exome sequencing identifies a novel prothrombin (F2) gene mutation in a Dutch Caucasian family with unexplained thrombosis

Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
Surgical Research Laboratory and Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam and Amsterdam UMC, University of Amsterdam, Department of Experimental Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands
Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK
Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
Department of Hematology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands
Vol. 105 No. 7 (2020): July, 2020 https://doi.org/10.3324/haematol.2019.232504