The effect of subsequent therapies in patients with chronic lymphocytic leukemia previously treated with prednisone and either cladribine or chlorambucil
T Robak, JZ Blonski, M Kasznicki, J Gora-Tybor, A Dmoszynska, A Skotnicki
Haematologica January 2005 90: 994-996; doi:

Author Affiliations

  1. T Robak,
  2. JZ Blonski,
  3. M Kasznicki,
  4. J Gora-Tybor,
  5. A Dmoszynska and
  6. A Skotnicki

Abstract

We present the long-term follow-up and results of subsequent treatments in patients with chronic lymphocytic leukemia treated initially with cladribine + prednisone or chlorambucil + prednisone in a randomized, cross-over study. We found higher complete and overall responses rates in patients who received cladribine + prednisone as first and second-line treatment but no significant differences in survival.

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