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Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
Department of Medical Genetics, School of Basic Medicine, Peking Union Medical College, Beijing, China;State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China;Department of Haematology, Cambridge University Hospitals NHS Trust, UK
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK;School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Australia;PathWest Division of Clinical Pathology, Queen Elizabeth II Medical Centre, Nedlands, Australia
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
Takeda Pharmaceuticals International, Cambridge, MA, USA
Instituto de Biomedicina y Biotecnología de Cantabria, Santander, Spain
Department of Medical Genetics, School of Basic Medicine, Peking Union Medical College, Beijing, China;State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK;Department of Haematology, Cambridge University Hospitals NHS Trust, UK
Vol. 101 No. 8 (2016): August, 2016 https://doi.org/10.3324/haematol.2016.146159