Articles

Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression

1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 2IRCCS Istituto Tumori Giovanni Paolo II of Bari, Italy; 3University of Bari Aldo Moro Medical School, Bari, Italy;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany;
3University of Bari Aldo Moro Medical School, Bari, Italy;
4Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy;
5Department of Pathology, University of Kiel/University Hospital Schleswig-Holstein, Kiel, Germany; Department of Pathophysiology and Transplantation, University of Milan and Fondazione IRCCS, Ca' Granda, Milan, Italy;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 7Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg, Würzburg, Germany;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 7Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg, Würzburg, Germany;
3University of Bari Aldo Moro Medical School, Bari, Italy;
8Department of Biomedical Science and Human Oncology, University of Aldo Moro Medical School, Bari, Italy;
8Department of Biomedical Science and Human Oncology, University of Aldo Moro Medical School, Bari, Italy;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany;
9Department of Molecular Medicine, University of Pavia, Pavia, Italy 10Department of Biomedical Engineering, Tufts University, Medford, MA, USA;
3University of Bari Aldo Moro Medical School, Bari, Italy;
11Molecular Diagnostics and Pharmacogenetics Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy;
2IRCCS Istituto Tumori;
12Institute of Pathology, University of Würzburg, Würzburg, Germany;
3University of Bari Aldo Moro Medical School, Bari, Italy;
2IRCCS Istituto Tumori;
13Institute of Anatomy and Cell Biology, Julius-Maximilians Universität Würzburg, Würzburg, Germany;
5Department of Pathology, University of Kiel/University Hospital Schleswig-Holstein, Kiel, Germany;
3University of Bari Aldo Moro Medical School, Bari, Italy;
14Institute of Hematology L. and A. Seràgnoli, Bologna, Italy;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany;
12Institute of Pathology, University of Würzburg, Würzburg, Germany;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany;
14Institute of Hematology L. and A. Seràgnoli, Bologna, Italy;
15Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Aldo Moro Medical School, Bari, Italy
3University of Bari Aldo Moro Medical School, Bari, Italy;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany;
3University of Bari Aldo Moro Medical School, Bari, Italy;
1Department of Medicine II, University Hospital of Würzburg, Würzburg, Germany; 7Interdisciplinary Center for Clinical Research Laboratory, University Hospital of Würzburg, Würzburg, Germany;
Vol. 106 No. 7 (2021): July, 2021 https://doi.org/10.3324/haematol.2019.239913