Editorials and Perspectives:

Mario Cazzola

Somatic mutations of JAK2 exon 12 as a molecular basis of erythrocytosis
Haematologica 2007 92: 1585-1589. [Full Text] [PDF]  

Sigbjørn Berentsen

Rituximab for the treatment of autoimmune cytopenias
Haematologica 2007 92: 1589-1596. [Full Text] [PDF]  

Fabio Efficace, Andrei Novik, Marco Vignetti, Franco Mandelli, Charles S. Cleeland

Health-related quality of life and symptom assessment in clinical research of patients with hematologic malignancies: where are we now and where do we go from here?
Haematologica 2007 92: 1596-1598. [Full Text] [PDF]  

Original Articles:

Red Cell Disorders:

Yesim Aydinok, Zulal Ulger, Deniz Nart, Aysen Terzi, Nurten Cetiner, Gareth Ellis, Arthur Zimmermann, Chantal Manz

A randomized controlled 1-year study of daily deferiprone plus twice weekly desferrioxamine compared with daily deferiprone monotherapy in patients with thalassemia major
Haematologica 2007 92: 1599-1606. [Abstract] [Full Text] [PDF]  

Myeloproliferative Disorders:

Melanie J. Percy, Linda M. Scott, Wendy N. Erber, Claire N. Harrison, John T. Reilly, Frank G.C. Jones, Anthony R. Green, Mary Frances McMullin

The frequency of JAK2 exon 12 mutations in idiopathic erythrocytosis patients with low serum erythropoietin levels
Haematologica 2007 92: 1607-1614. [Abstract] [Full Text] [PDF]  

Acute Promyelocytic Leukemia:

Gil Cunha De Santis, Mirela de Barros Tamarozzi, Romualdo Barroso Sousa, Susana Elisa Moreno, Daniela Secco, Aglair Bergamo Garcia, Ana Sílvia Gouveia Lima, Lúcia Helena Faccioli, Roberto Passetto Falcão, Fernando Queirós Cunha, Eduardo Magalhães Rego

Adhesion molecules and differentiation syndrome: phenotypic and functional analysis of the effect of ATRA, As₂O₃, phenylbutyrate, and G-CSF in acute promyelocytic leukemia
Haematologica 2007 92: 1615-1622. [Abstract] [Full Text] [PDF]  

Malignant Lymphomas:

Mathilde Hunault, Malgorzata Truchan-Graczyk, Denis Caillot, Jean-Luc Harousseau, Serge Bologna, Chantal Himberlin, Denis Guyotat, Christian Berthou, Philippe Casassus, Laurence Baranger, Marie-Christine Béné, Norbert Ifrah, Emmanuel Gyan for the GOELAMS Group

Outcome of adult T-lymphoblastic lymphoma after acute lymphoblastic leukemia-type treatment: a GOELAMS trial
Haematologica 2007 92: 1623-1630. [Abstract] [Full Text] [PDF]  

Lymphoproliferative Disorders:

Antonio F. Santidrián, Ana M. Cosialls, Llorenç Coll-Mulet, Daniel Iglesias-Serret, Mercè de Frias, Diana M. González-Gironès, Clara Campàs, Alicia Domingo, Gabriel Pons, Joan Gil

The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells
Haematologica 2007 92: 1631-1638. [Abstract] [Full Text] [PDF] [Supplementary data - Design and Methods]  

Disorders of Hemostasis:

Lucia Rugeri, Suzette Beguin, Coenraad Hemker, Jean-Claude Bordet, Raphael Fleury, Brigitte Chatard, Claude Negrier, Yesim Dargaud

Thrombin-generating capacity in patients with von Willebrand’s disease
Haematologica 2007 92: 1639-1646. [Abstract] [Full Text] [PDF]  

Silvia Giannini, Anna Maria Mezzasoma, Mario Leone, Paolo Gresele

Laboratory diagnosis and monitoring of desmopressin treatment of von Willebrand’s disease by flow cytometry
Haematologica 2007 92: 1647-1654. [Abstract] [Full Text] [PDF]  

Stem Cell Transplantation:

Carme Talarn, Alvaro Urbano-Ispizua, Rodrigo Martino, José Antonio Pérez-Simón, Montserrat Batlle, Concepción Herrera, Miquel Granell, Anna Gaya, Montserrat Torrebadell, Francesc Fernández-Avilés, Marta Aymerich, Pedro Marín, Jorge Sierra, Emili Montserrat

Kinetics of recovery of dendritic cell subsets after reduced-intensity conditioning allogeneic stem cell transplantation and clinical outcome
Haematologica 2007 92: 1655-1663. [Abstract] [Full Text] [PDF]  

Transfusion Medicine:

Paola Manzini, Mauro Girotto, Raffaele Borsotti, Osvaldo Giachino, Roberto Guaschino, Maurizio Lanteri, Domenico Testa, Paola Ghiazza, Maria Vacchini, Franca Danielle, Alessandra Pizzi, Chiara Valpreda, Franco Castagno, Franco Curti, Paola Magistroni, Maria Lorena Abate, Antonina Smedile, Mario Rizzetto

Italian blood donors with anti-HBc and occult hepatitis B virus infection
Haematologica 2007 92: 1664-1670. [Abstract] [Full Text] [PDF]  

Cell Therapy and Immunotherapy:

Jeltje F. de Vries, Peter A. von dem Borne, Simone A.P. van Luxemburg-Heijs, Mirjam H.M. Heemskerk, Roel Willemze, J.H. Frederik Falkenburg, Renèe M.Y. Barge

Differential activation of the death receptor pathway in human target cells induced by cytotoxic T lymphocytes showing different kinetics of killing
Haematologica 2007 92: 1671-1678. [Abstract] [Full Text] [PDF]  

Decision Making and Problem Solving:

Stem Cell Transplantation:

Alois Gratwohl, Helen Baldomero, Alvin Schwendener, Michael Gratwohl, Jane Apperley, Dietger Niederwieser, Karl Frauendorfer for the Joint Accreditation Committee of the International Society for Cellular Therapy (ISCT), the European Group for Blood and Marrow Transplantation (EBMT) (JACIE) and for the European Leukemia Net

Predictability of hematopoietic stem cell transplantation rates
Haematologica 2007 92: 1679-1686. [Abstract] [Full Text] [PDF]  

Brief Reports:

Aplastic Anemia:

Yuko Osugi, Hiroshi Yagasaki, Masahiro Sako, Yoshiyuki Kosaka, Takashi Taga, Tsuyoshi Ito, Masuji Yamamoto, Akira Ohara, Takeyuki Sato, Junichi Mimaya, Ichiro Tsukimoto, Seiji Kojima, the Japan Childhood Aplastic Anemia Study Group

Antithymocyte globulin and cyclosporine for treatment of 44 children with hepatitis associated aplastic anemia
Haematologica 2007 92: 1687-1690. [Abstract] [Full Text] [PDF]  

Autoimmune Cytopenias:

Brigitte Bader-Meunier, Nathalie Aladjidi, Françoise Bellmann, Fabrice Monpoux, Brigitte Nelken, Alain Robert, Corinne Armari-Alla, Capucine Picard, Françoise Ledeist, Martine Munzer, Karima Yacouben, Yves Bertrand, Antoine Pariente, Arnaud Chaussé, Yves Perel, Guy Leverger

Rituximab therapy for childhood Evans syndrome
Haematologica 2007 92: 1691-1694. [Abstract] [Full Text] [PDF] [Supplementary Figure]  

Drew Provan, Tom Butler, Maria Laura Evangelista, Sergio Amadori, Adrian C. Newland, Roberto Stasi

Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults
Haematologica 2007 92: 1695-1698. [Abstract] [Full Text] [PDF]  

Acute Lymphoblastic Leukemia:

Thomas Burmeister, Stefan Schwartz, Almut Taubald, Edgar Jost, Thomas Lipp, Folker Schneller, Helmut Diedrich, Henrike Thomssen, Ulrich J.M. Mey, Jan Eucker, Harald Rieder, Nicola Gökbuget, Dieter Hoelzer, Eckhard Thiel

Atypical BCR-ABL mRNA transcripts in adult Acute lymphoblastic leukemia
Haematologica 2007 92: 1699-1702. [Abstract] [Full Text] [PDF]  

Thrombosis:

Willem M. Lijfering, Nic J.G.M. Veeger, Jan-Leendert P. Brouwer, Jan van der Meer

The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels
Haematologica 2007 92: 1703-1706. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Hematopoietic Cells:

Andrew C.W. Zannettino, Sharon Paton, Angela Kortesidis, Fiona Khor, Silviu Itescu, Stan Gronthos

Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1^bright/CD34^–/CD45^–/glycophorin-A-bone marrow cells
Haematologica 2007 92: 1707-1708. [Abstract] [Full Text] [PDF]  

Red Cell Disorders:

Mariane de Montalembert, Yacine Aggoun, Assa Niakate, Isabelle Szezepanski, Damien Bonnet

Endothelial-dependent vasodilation is impaired in children with sickle cell disease
Haematologica 2007 92: 1709-1710. [Abstract] [Full Text] [PDF]  

Anne L. Morkbak*, Anne-Mette Hvas, Nils Milman, Ebba Nexo

Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum
Haematologica 2007 92: 1711-1712. [Abstract] [Full Text] [PDF]  

Licínio Manco, Paula Gonçalves, Patrícia Antunes, Filomena Maduro, Augusto Abade, M. Letícia Ribeiro

Mutations and haplotype diversity in 70 Portuguese G6PD-deficient individuals: an overview on the origin and evolution of mutated alleles
Haematologica 2007 92: 1713-1714. [Abstract] [Full Text] [PDF]  

Neeraj Agarwal, Ferdane Kutlar, Mariluz P. Mojica-Henshaw, Ching N. Ou, Amos Gaikwad, N. Scott Reading, Lakeia Bailey, Abdullah Kutlar, Josef T. Prchal

Missense mutation of the last nucleotide of exon 1 (G->C) of β globin gene not only leads to undetectable mutant peptide and transcript but also interferes with the expression of wild allele
Haematologica 2007 92: 1715-1716. [Abstract] [Full Text] [PDF] [Agarwal et al. Design and Methods]  

Myeloproliferative Disorders:

Luz Martínez-Avilés, Carles Besses, Alberto Álvarez-Larrán, Francisco Cervantes, Juan Carlos Hernández-Boluda, Beatriz Bellosillo

JAK2 exon 12 mutations in polycythemia vera or idiopathic erythrocytosis
Haematologica 2007 92: 1717-1718. [Abstract] [Full Text] [PDF]  

Acute Myeloid Leukemia:

Marie von Lilienfeld-Toal, Corinna Hahn-Ast, Hartmut Kirchner, Dimitri Flieger, Gottfried Dölken, Axel Glasmacher

A randomized comparison of immediate versus delayed application of G-CSF in induction therapy for patients with acute myeloid leukemia unfit for intensive chemotherapy
Haematologica 2007 92: 1719-1720. [Abstract] [Full Text] [PDF] [Supplementary data]  

Pier Paolo Piccaluga, Michele Malagola, Michela Rondoni, Mario Arpinati, Stefania Paolini, Anna Candoni, Renato Fanin, Emanuela Messa, Maria Teresa Pirrotta, Francesco Lauria, Giuseppe Visani, Daniele Alberti, Francesca Rancati, Vincenza Vinaccia, Domenico Russo, Giuseppe Saglio, Michele Baccarani, Giovanni Martinelli

Imatinib mesylate in the treatment of newly diagnosed or refractory/resistant c-KIT positive acute myeloid leukemia. Results of an italian multicentric phase II study.
Haematologica 2007 92: 1721-1722. [Abstract] [Full Text] [PDF]  

Acute Lymphoblastic Leukemia:

José Luis Fuster, Mar Bermúdez, Ana Galera, María Esther Llinares, Doris Calle, Francisco Jose Ortuño

Imatinib mesylate in combination with chemotherapy in four children with de novo and advanced stage Philadelphia chromosome-positive acute lymphoblastic leukemia
Haematologica 2007 92: 1723-1724. [Abstract] [Full Text] [PDF]  

Disorders of Hemostasis:

Atreyee Saha, Saibal Mukherjee, Mahua Maulik, Giriraj Ratan Chandak, The Indian Genome Variation Consortium, Kunal Ray

Evaluation of genetic markers linked to hemophilia A locus: an Indian experience
Haematologica 2007 92: 1725-1726. [Abstract] [Full Text] [PDF]  

Stem Cell Transplantation:

Yoichiro Tsuji, Kohsuke Imai, Yoichi Morinishi, Kazuhiro Kogawa, Masaaki Morino, Shigeaki Nonoyama

Successful unrelated cord blood transplantation for a patient with CD40 ligand deficiency
Haematologica 2007 92: 1727-1728. [Abstract] [Full Text] [PDF]  

Online Only Articles:

T. Linden, J. Gerss, H. Jürgens

The crux of the log rank test. Re: Locasciulli A, Oneto R, Bacigalupo A, Socié G, Korthof E, Bekassy A, Schrezenmeier H, Passweg J, Führer M. Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade: a report from the European Group for Blood and Marrow Transplantation. Haematologica 2007; 92:11-8
Haematologica 2007 92: e122. [Full Text] [PDF]  

K. Matsubara, K. Imai, S. Okada, M. Miki, N. Ishikawa, M. Tsumura, T. Kato, O. Ohara, S. Nonoyama, M. Kobayashi

Severe developmental delay and epilepsy in a Japanese patient with severe congenital neutropenia due to HAX1 deficiency
Haematologica 2007 92: e123-e125. [Abstract] [Full Text] [PDF]  

M.T. Krauth, M. Födinger, L. Rebuzzi, R. Greul, A. Chott, P. Valent

Aggressive systemic mastocytosis with sarcoma-like growth in the skeleton, leukemic progression, and partial loss of mast cell differentiation antigens
Haematologica 2007 92: e126-e129. [Full Text] [PDF]  

E. van der Spek, A.C. Bloem, H.A. Sinnige, H.M. Lokhorst

High dose Simvastatin does not reverse resistance to Vincristine, Adriamycin, and Dexamethasone (VAD) in Myeloma
Haematologica 2007 92: e130-e131. [Abstract] [Full Text] [PDF]  

F. Noizat-Pirenne, D. Bachir, P. Chadebech, M. Michel, A. Plonquet, J.-C. Lecron, F. Galactéros, P. Bierling

Rituximab for prevention of delayed hemolytic transfusion reaction in sickle cell disease
Haematologica 2007 92: e132-e135. [Abstract] [Full Text] [PDF] [Correction]  

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