6 October 2008

Risk factors and decision criteria for intensive chemotherapy in older patients with acute myeloid leukemia

Jean-Valère Malfuson, Anne Etienne, Pascal Turlure, Thierry de Revel, Xavier Thomas, Nathalie Contentin, Christine Terré, Sophie Rigaudeau, Dominique Bordessoule, Norbert Vey, Claude Gardin, Hervé Dombret, and for the Acute Leukemia French Association (ALFA)
Haematologica published October 6, 2008 as doi:10.3324/haematol.13309 [Abstract] [PDF]  

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

Roel G.W. Verhaak, Bas J. Wouters, Claudia A.J. Erpelinck, Saman Abbas, H. Berna Beverloo, Sanne Lugthart, Bob Löwenberg, Ruud Delwel, and Peter J.M. Valk
Haematologica published October 6, 2008 as doi:10.3324/haematol.13299 [Abstract] [PDF] [Verhaak et al. - Supplementary Appendix]  

Consensus conference on the management of tumor lysis syndrome

Patrizia Tosi, Giovanni Barosi, Carlo Lazzaro, Vincenzo Liso, Monia Marchetti, Enrica Morra, Andrea Pession, Giovanni Rosti, Antonio Santoro, Pier Luigi Zinzani, and Sante Tura
Haematologica published October 6, 2008 as doi:10.3324/haematol.13290 [Abstract] [PDF]  

Autologous stem cell transplantation in elderly patients ( 60 years) with diffuse large B-cell lymphoma: an analysis based on data in the European Blood and Marrow Transplantation registry

Esa Jantunen, Carmen Canals, Alessandro Rambaldi, Gert Ossenkoppele, Bernardino Allione, Didier Blaise, Eulogio Conde, Hervè Tilly, Gordon Cook, Fiona Clark, Andrea Gallamini, Andrew Haynes, Nicolas Mounier, Peter Dreger, Michael Pfreundschuh, Anna Sureda, and for the EBMT Lymphoma Working Party
Haematologica published October 6, 2008 as doi:10.3324/haematol.13273 [Abstract] [PDF]  

Identification of different Ikaros cDNA transcripts in Philadelphia-positive adult acute lymphoblastic leukemia by a high-throughput capillary electrophoresis sizing method

Ilaria Iacobucci, Annalisa Lonetti, Daniela Cilloni, Francesca Messa, Anna Ferrari, Roberta Zuntini, Simona Ferrari, Emanuela Ottaviani, Francesca Arruga, Stefania Paolini, Cristina Papayannidis, Pier Paolo Piccaluga, Simona Soverini, Giuseppe Saglio, Fabrizio Pane, Anna Baruzzi, Marco Vignetti, Giorgio Berton, Antonella Vitale, Sabina Chiaretti, Markus Müschen, Robin Foà, Michele Baccarani, and Giovanni Martinelli
Haematologica published October 6, 2008 as doi:10.3324/haematol.13260 [Abstract] [PDF] [Iacobucci et al. - Supplementary Appendix]  

Chromosomal instability syndromes are sensitive to poly ADP ribose polymerase inhibitors

Terry J. Gaymes, Sydney Shall, Farzin Farzaneh, and Ghulam J. Mufti
Haematologica published October 6, 2008 as doi:10.3324/haematol.13201 [Abstract] [PDF] [Gaymes et al. - Supplementary Appendix]  

Chronic myeloid leukemia in blast crisis treated with imatinib 600 mg: outcome of the patients alive after a 6-year follow-up

Francesca Palandri, Fausto Castagnetti, Nicoletta Testoni, Simona Luatti, Giulia Marzocchi, Simona Bassi, Massimo Breccia, Giuliana Alimena, Ester Pungolino, Giovanna Rege-Cambrin, Riccardo Varaldo, Maurizio Miglino, Giorgina Specchia, Eliana Zuffa, Felicetto Ferrara, Monica Bocchia, Giuseppe Saglio, Fabrizio Pane, Daniele Alberti, Giovanni Martinelli, Michele Baccarani, Gianantonio Rosti, and on behalf of the GIMEMA Working Party on chronic myeloid leukemia
Haematologica published October 6, 2008 as doi:10.3324/haematol.13068 [Abstract] [PDF]  

Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity

Désirée Bonci, Maria Musumeci, Valeria Coppola, Antonio Addario, Concetta Conticello, Michael Hahne, Massimo Gulisano, Francesco Grignani, and Ruggero De Maria
Haematologica published October 6, 2008 as doi:10.3324/haematol.13035 [Abstract] [PDF] [Bonci et al. - Supplementary Appendix]  

Autoimmune conditions and chronic infections in chronic lymphocytic leukemia patients at diagnosis are associated with unmutated IgV_H genes

Katrina Vanura, Trang Le, Harald Esterbauer, Florentin Späth, Edit Porpaczy, Medhat Shehata, Karin Eigenberger, Alexander Hauswirth, Cathrin Skrabs, Elisabeth Krömer, Ilse Schwarzinger, Berthold Streubel, Christoph Steininger, Christa Fonatsch, Stephan Stilgenbauer, Oswald Wagner, Alexander Gaiger, and Ulrich Jäger
Haematologica published October 6, 2008 as doi:10.3324/haematol.12955 [Abstract] [PDF] [Vanura et al. - Supplementary Appendix]  

Diagnosis and classification of myelodysplastic syndrome: International Working Group on Morphology of Myelodysplastic Syndrome (IWGM-MDS) consensus proposals for the definition and enumeration of myeloblasts and ring sideroblasts

Ghulam J. Mufti, John M. Bennett, Jean Goasguen, Barbara J. Bain, Irith Baumann, Richard Brunning, Mario Cazzola, Pierre Fenaux, Ulrich Germing, Eva Hellström-Lindberg, Itsuro Jinnai, Atsushi Manabe, Akira Matsuda, Charlotte M. Niemeyer, Guillermo Sanz, Masao Tomonaga, Teresa Vallespi, and Ayami Yoshimi
Haematologica published October 6, 2008 as doi:10.3324/haematol.13405 [Abstract] [PDF]  

2 October 2008

Multiplex ligation-dependent probe amplification (MLPA) enhances molecular diagnosis of Diamond-Blackfan anemia due to RPS19 deficiency

Paola Quarello, Emanuela Garelli, Alfredo Brusco, Adriana Carando, Patrizia Pappi, Marco Barberis, Valentina Coletti, Maria Francesca Campagnoli, Irma Dianzani, and Ugo Ramenghi
Haematologica published October 2, 2008 as doi:10.3324/haematol.13423 [PDF]  

Impact of genotype on survival of children with T-cell acute lymphoblastic leukemia treated according to the French protocol FRALLE-93: the effect of TLX3/HOX11L2 gene expression on outcome

Paola Ballerini, Judith Landman-Parker, Jean Michel Cayuela, Vahid Asnafi, Myriam Labopin, Virginie Gandemer, Yves Perel, Gérard Michel, Thierry Leblanc, Claudine Schmitt, Sylvie Fasola, Anne Hagemejier, François Sigaux, Marie Françoise Auclerc, Luc Douay, Guy Leverger, and André Baruchel
Haematologica published October 2, 2008 as doi:10.3324/haematol.13291 [Abstract] [PDF] [Ballerini et al. - Supplementary Appendix]  

Nonsense-mediated mRNA decay in the ADAMTS13 gene caused by a 29-nucleotide deletion

Isabella Garagiola, Carla Valsecchi, Silvia Lavoretano, Hale Oren, Martina Bohm, and Flora Peyvandi
Haematologica published October 2, 2008 as doi:10.3324/haematol.13102 [Abstract] [PDF] [Garagiola et al. - Supplementary Appendix]  

Anthropometric characteristics and non-Hodgkin lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Julie A. Britton, Aneire E. Khan, Sabine Rohrmann, Nikolaus Becker, Jakob Linseisen, Alexandra Nieters, Rudolf Kaaks, Anne Tjønneland, Jytte Halkjær, Marianne Tang Severinsen, Kim Overvad, Tobias Pischon, Heiner Boeing, Antonia Trichopoulou, Victoria Kalapothaki, Dimitrios Trichopoulos, Amalia Mattiello, Giovanna Tagliabue, Carlotta Sacerdote, Petra H.M. Peeters, H. Bas Bueno-de-Mesquita, Eva Ardanaz, Carmen Navarro, Paula Jakszyn, Jone M. Altzibar, Göran Hallmans, Beatrice Malmer, Göran Berglund, Jonas Manjer, Naomi Allen, Timothy Key, Sheila Bingham, Hervé Besson, Pietro Ferrari, Mazda Jenab, Paolo Boffetta, Paolo Vineis, and Elio Riboli
Haematologica published October 2, 2008 as doi:10.3324/haematol.13078 [Abstract] [PDF]  

Impact of AB0-blood group incompatibility on the outcome of recipients of bone marrow transplants from unrelated donors in the Japan Marrow Donor Program

Fumihiko Kimura, Ken Sato, Shinichi Kobayashi, Takashi Ikeda, Hiroshi Sao, Shinichiro Okamoto, Koichi Miyamura, Shin-ichiro Mori, Hideki Akiyama, Makoto Hirokawa, Hitoshi Ohto, Hiroshi Ashida, Kazuo Motoyoshi, and for The Japan Marrow Donor Program
Haematologica published October 2, 2008 as doi:10.3324/haematol.12933 [Abstract] [PDF]  

24 September 2008

Nonsense mutations of the -spectrin gene in hereditary pyropoikilocytosis

Whitney Tolpinrud, Yelena D. Maksimova, Bernard G. Forget, and Patrick G. Gallagher
Haematologica published September 24, 2008 as doi:10.3324/haematol.13639 [PDF]  

Enhanced alternative splicing of the FLVCR1 gene in Diamond Blackfan anemia disrupts FLVCR1 expression and function that are critical for erythropoiesis

Michelle A. Rey, Simon P. Duffy, Jennifer K. Brown, James A. Kennedy, John E. Dick, Yigal Dror, and Chetankumar S. Tailor
Haematologica published September 24, 2008 as doi:10.3324/haematol.13359 [Abstract] [PDF]  

Anemia of chronic disease and defective erythropoietin production in patients with celiac disease

Gaetano Bergamaschi, Konstantinos Markopoulos, Riccardo Albertini, Antonio Di Sabatino, Federico Biagi, Rachele Ciccocioppo, Eloisa Arbustini, and Gino Roberto Corazza
Haematologica published September 24, 2008 as doi:10.3324/haematol.13255 [Abstract] [PDF]  

The relevance of preferentially expressed antigen of melanoma (PRAME) as a marker of disease activity and prognosis in acute promyelocytic leukemia

Carlos Santamaría, María Carmen Chillón, Ramón García-Sanz, Ana Balanzategui, María Eugenia Sarasquete, Miguel Alcoceba, Fernando Ramos, Teresa Bernal, José Antonio Queizán, María Jesús Peñarrubia, Pilar Giraldo, Jesús F. San Miguel, and Marcos Gonzalez
Haematologica published September 24, 2008 as doi:10.3324/haematol.13214 [Abstract] [PDF]  

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

An De Weer, Frank Speleman, Barbara Cauwelier, Nadine Van Roy, Nurten Yigit, Bruno Verhasselt, Barbara De Moerloose, Yves Benoit, Lucien Noens, Dominik Selleslag, Eric Lippert, Stephanie Struski, Christian Bastard, Anne De Paepe, Peter Vandenberghe, Anne Hagemeijer, Nicole Dastugue, Bruce Poppe, and on behalf of the Groupe Français de Cytogénétique Hématologique (GFCH)
Haematologica published September 24, 2008 as doi:10.3324/haematol.13192 [Abstract] [PDF]  

Anemia and survival in childhood acute lymphoblastic leukemia

Oliver Teuffel, Martin Stanulla, Gunnar Cario, Wolf D. Ludwig, Silja Rottgers, Beat W. Schafer, Martin Zimmermann, Martin Schrappe, and Felix K. Niggli
Haematologica published September 24, 2008 as doi:10.3324/haematol.13156 [Abstract] [PDF]  

Asthma is associated with acute chest syndrome, but not with an increased rate of hospitalization for pain among children in France with sickle cell anemia: a retrospective cohort study

Francoise Bernaudin, Robert C. Strunk, Annie Kamdem, Cecile Arnaud, Ping An, Martine Torres, Christophe Delacourt, and Michael R. DeBaun
Haematologica published September 24, 2008 as doi:10.3324/haematol.13090 [PDF]  

Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders

Nasios Fourouclas, Juan Li, Daniel C. Gilby, Peter J. Campbell, Philip A. Beer, Elaine M. Boyd, Anne C. Goodeve, David Bareford, Claire N. Harrison, John T. Reilly, Anthony R. Green, and Anthony J. Bench
Haematologica published September 24, 2008 as doi:10.3324/haematol.13043 [Abstract] [PDF]  

Novel point mutation in a leucine-rich repeat of the GPIb chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome affecting two unrelated families: the N41H variant

Silvia Vettore, Raffaella Scandellari, Stefano Moro, Anna Maria Lombardi, Margherita Scapin, Maria Luigia Randi, and Fabrizio Fabris
Haematologica published September 24, 2008 as doi:10.3324/haematol.12830 [Abstract] [PDF] [Vettore et al. - Supplementary data]  

11 September 2008

Immune-mediated pure red cell aplasia in renal transplant recipients

Julien Zuber, Kheira Beldjord, Nicole Casadevall, Eric Thervet, Christophe Legendre, and Bruno Varet
Haematologica published September 11, 2008 as doi:10.3324/haematol.13477 [PDF]  

Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients

Francesco Passamonti, Elisa Rumi, Luca Arcaini, Emanuela Boveri, Chiara Elena, Daniela Pietra, Sabrina Boggi, Cesare Astori, Paolo Bernasconi, Marzia Varettoni, Ercole Brusamolino, Cristiana Pascutto, and Mario Lazzarino
Haematologica published September 11, 2008 as doi:10.3324/haematol.13346 [Abstract] [PDF]  

Monitoring for cytomegalovirus and Epstein-Barr virus infection in chronic lymphocytic leukemia patients receiving i.v. fludarabine-cyclophosphamide combination and alemtuzumab as consolidation therapy

Ester M. Orlandi, Fausto Baldanti, Annalisa Citro, Lara Pochintesta, Marta Gatti, and Mario Lazzarino
Haematologica published September 11, 2008 as doi:10.3324/haematol.13265 [PDF]  

The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders

Alexandre Theocharides, Jakob R. Passweg, Michael Medinger, Renate Looser, Sai Li, Hui Hao-Shen, Andreas S. Buser, Alois Gratwohl, André Tichelli, and Radek C. Skoda
Haematologica published September 11, 2008 as doi:10.3324/haematol.13074 [Abstract] [PDF]  

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO

Tobias Berg, Manfred Fliegauf, Jan Burger, Martin S. Staege, Shaohua Liu, Natalia Martinez, Olaf Heidenreich, Stefan Burdach, Torsten Haferlach, Milton H. Werner, and Michael Lübbert
Haematologica published September 11, 2008 as doi:10.3324/haematol.13044 [Abstract] [PDF] [Berg et al. - Supplementary Data]  

2 September 2008

Controlling -globin: a review of -globin expression and its Impact on β-thalassemia

Hsiao Phin Joanna Voon and Jim Vadolas
Haematologica published September 2, 2008 as doi:10.3324/haematol.13490 [Abstract] [PDF]  

Prospective comparison of subcutaneous versus intravenous administration of bortezomib in patients with multiple myeloma

Philippe Moreau, Valerie Coiteux, Cyrille Hulin, Xavier Leleu, Helgi van de Velde, Milin Acharya, and Jean-Luc Harousseau
Haematologica published September 2, 2008 as doi:10.3324/haematol.13285 [Abstract] [PDF] [Moreau et al.- Supplementary Appendix]  

Hematopoietic stem cell transplantation for hemophagocytic lymphohistiocytosis: a retrospective analysis of data from the Italian Association of Pediatric Hematology Oncology (AIEOP)

Simone Cesaro, Franco Locatelli, Edoardo Lanino, Fulvio Porta, Lucia Di Maio, Chiara Messina, Arcangelo Prete, Mimmo Ripaldi, Natasha Maximova, Giovanna Giorgiani, Roberto Rondelli, Maurizio Aricò, and Franca Fagioli
Haematologica published September 2, 2008 as doi:10.3324/haematol.13142 [Abstract] [PDF]  

Long term biweekly 1 mg oral vitamin B₁₂ ensures normal hematological parameters, but does not correct all other markers of vitamin B₁₂ deficiency. A study in patients with inherited vitamin B₁₂ deficiency

Mustafa Vakur Bor, Mualla Çetin, Selin Aytaç, Çigdem Altay, Per Magne Ueland, and Ebba Nexo
Haematologica published September 2, 2008 as doi:10.3324/haematol.13122 [PDF]  

High INDO (indoleamine 2,3-dioxygenase) mRNA level in blasts of acute myeloid leukemic patients predicts poor clinical outcome

Martine E.D. Chamuleau, Arjan A. van de Loosdrecht, Corine J. Hess, Jeroen J.W.M. Janssen, Adri Zevenbergen, Ruud Delwel, Peter J.M. Valk, Bob Löwenberg, and Gert J. Ossenkoppele
Haematologica published September 2, 2008 as doi:10.3324/haematol.13112 [Abstract] [PDF]  

Study of the effects of proteasome inhibitors on ribosomal protein S19 mutants, identified in patients with Diamond-Blackfan anemia

Aurore Crétien, Corinne Hurtaud, Hélène Moniz, Alexis Proust, Isabelle Marie, Orianne Wagner-Ballon, Valérie Choesmel, Pierre-Emmanuel Gleizes, Thierry Leblanc, Jean Delaunay, Gil Tchernia, Narla Mohandas, and Lydie Da Costa
Haematologica published September 2, 2008 as doi:10.3324/haematol.13023 [Abstract] [PDF]  

25 August 2008

B-cell involvement in chronic graft-versus-host disease

Rick Kapur, Saskia Ebeling, and Anton Hagenbeek
Haematologica published August 25, 2008 as doi:10.3324/haematol.13311 [Abstract] [PDF]  

First case of -thalassemia in association with a βS allele: a pitfall in the neonatal screening for sickle cell disease

Caroline Lacoste, Nathalie Bonello-Palot, Katia Gonnet, Françoise Merono, Nicolas Levy, Isabelle Thuret, and Catherine Badens
Haematologica published August 25, 2008 as doi:10.3324/haematol.13262 [PDF]  

An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell ALL: a multi-center study of 381 patients

Hareth Nahi, Hans Hägglund, Thomas Ahlgren, Per Bernell, Mats Hardling, Karin Karlsson, Vladimir Lj Lazarevic, Mats Linderholm, Bengt Smedmyr, Maria Åström, and Helene Hallböök
Haematologica published August 25, 2008 as doi:10.3324/haematol.13227 [Abstract] [PDF]  

Imatinib and leptomycin B are effective in overcoming imatinib-resistance due to Bcr-Abl amplification and clonal evolution but not due to Bcr-Abl kinase domain mutation

Rama Krishna Kancha, Nikolas von Bubnoff, Cornelius Miething, Christian Peschel, Katharina S. Götze, and Justus Duyster
Haematologica published August 25, 2008 as doi:10.3324/haematol.13207 [Abstract] [PDF]  

Mobilization of peripheral blood stem cells in myeloma with either pegfilgrastim or filgrastim following chemotherapy

Guido Tricot, Bart Barlogie, Maurizio Zangari, Frits van Rhee, Antje Hoering, Jackie Szymonifka, and Michele Cottler-Fox
Haematologica published August 25, 2008 as doi:10.3324/haematol.13204 [Abstract] [PDF]  

Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2V617F-positive patients within the first years of hydroxyurea therapy

François Girodon, Céline Schaeffer, Cédric Cleyrat, Morgane Mounier, Ingrid Lafont, Frédéric Dos Santos, Aurélie Vidal, Marc Maynadié, and Sylvie Hermouet
Haematologica published August 25, 2008 as doi:10.3324/haematol.13081 [Abstract] [PDF]  

12 August 2008

Increased cytotoxic T-lymphocyte-mediated cytotoxicity predominant in idiopathic thrombocytopenic purpura patients without platelet autoantibodies

Chunhong Zhao, Xiaofang Li, Feng Zhang, Lin Wang, Jun Peng, and Ming Hou
Haematologica published August 12, 2008 as doi:10.3324/haematol.12889. [PDF]  

Outcome for children with relapsed acute myeloid leukemia in the Netherlands following initial treatment between 1980 and 1998: survival after chemotherapy only?

Bianca F. Goemans, Rienk Y.J. Tamminga, Carin M. Corbijn, Karel Hählen, and GertJan J.L. Kaspers
Haematologica published August 12, 2008 as doi:10.3324/haematol.12807. [PDF]  

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