CURRENT ISSUE
September, 2025
No. 110 (9)

Landmark papers in Hematology

Editorials

Review Articles

Review Series

Pediatric acute leukemias and myelodysplastic syndromes

Articles

Acute Lymphoblastic Leukemia

Long-term kidney complications in childhood leukemia survivors: a study from the Childhood and Adolescent Leukemia (LEA) project (1611 Online Views)

Carine Domenech, Paul Saultier, Zeinab Hamidou, Marie-Dominique Tabone, Marlène Pasquet, Virginie Gandemer, Stéphane Ducassou, Marilyne Poirée, Dominique Plantaz, Jean-Hugues Dalle, Pascal Chastagner, Sandrine Thouvenin, Justyna Kanold, Alexandre Theron, Isabelle Pellier, Yves Reguerres, André Baruchel, Pascal Auquier, Justine Bacchetta, Gérard Michel, Laurence Derain-Dubourg

https://doi.org/10.3324/haematol.2024.286940

Acute Myeloid Leukemia

Reduced incidence of relapse and graft-versus-host disease in acute myeloid leukemia after allogeneic hematopoietic cell transplantation (4081 Online Views)

Haesook T. Kim, Robert J. Soiffer, Corey Cutler, John Koreth, Sarah Nikiforow, Roman M. Shapiro, Amar Kelkar, Mahasweta Gooptu, Rizwan Romee, Catherine J. Wu, Joseph H. Antin, Jerome Ritz, Vincent T. Ho.

https://doi.org/10.3324/haematol.2025.287390

Enforcement of stem-cell dormancy by nucleophosmin mutation is a critical determinant of unrestricted self-renewal during myeloid leukemogenesis (1903 Online Views)

Maria Elena Boggio Merlo, Maria Mallardo, Lucilla Luzi, Giulia De Conti, Chiara Caprioli, Roman Hillje, Mario Faretta, Cecilia Restelli, Andrea Polazzi, Valentina Tabanelli, Angelica Calleri, Stefano Pileri, Pier Giuseppe Pelicci, Emanuela Colombo

https://doi.org/10.3324/haematol.2024.286577

Impact of hematopoietic cell transplantation and quizartinib in newly diagnosed patients with acute myeloid leukemia and FMS-like tyrosine kinase 3-internal tandem duplications in the QuANTUM-First trial (3480 Online Views)

Richard F. Schlenk, Pau Montesinos, Hee-Je Kim, Antonio Romero-Aguilar, Radovan Vrhovac, Elżbieta Patkowska, Pavel Žak, Po-Nan Wang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Karima Imadalou, Arnaud Lesegretain, Jorge Cortes, Mikkael A. Sekeres, Herve Dombret, Sergio Amadori, Jianxiang Wang, Alexander E. Perl, Mark J. Levis, Harry P. Erba

https://doi.org/10.3324/haematol.2024.286623

Cell Therapy & Immunotherapy

Real-world comparison of lisocabtagene maraleucel and axicabtagene ciloleucel in large B-cell lymphoma: an inverse probability of treatment weighting analysis with 3-year follow-up (5237 Online Views)

Andrew J. Portuguese, Jennifer J. Huang, Yein Jeon, Mahnoosh Taheri, Aya Albittar, Emily C. Liang, Alexandre V. Hirayama, Erik L. Kimble, Lorenzo Iovino, Christina Poh, Ajay K. Gopal, Mazyar Shadman, Brian G. Till, Filippo Milano, Aude G. Chapuis, Folashade Otegbeye, Ryan D. Cassaday, Ryan S. Basom, Qian Vicky Wu, David G. Maloney, Jordan Gauthier

https://doi.org/10.3324/haematol.2024.287010

Coagulation & its Disorders

Hemophilia is associated with accelerated biological aging (2477 Online Views)

Marina Trappl, Rafaela Vostatek, Manuel Salzmann, Daniel Kraemmer, Johanna Gebhart, Philipp Hohensinner, Ingrid Pabinger, Cihan Ay

https://doi.org/10.3324/haematol.2024.286421

Consistent clinical factor VIII equivalency is unlikely for non-factor therapies in hemophilic mice (2377 Online Views)

Thibaud Sefiane, Geneviève McCluskey, Marie Clavel, Hortense Maynadié, Ivan Peyron, Tovo David, Camille Brochier, François Saller, Mariem Khamari, Cécile V. Denis, Olivier D. Christophe, Peter J. Lenting, Vincent Muczynski, Caterina Casari

https://doi.org/10.3324/haematol.2024.286982

Hematopoiesis

Overall cancer risk in people with deleterious germline DDX41 variants (2375 Online Views)

Sophia C. Korotev, Jason X. Cheng, Yogameenakshi Haribabu, Joshua Strauss, Salina Dominguez, Ashwin Koppayi, Melody Perpich, Madeline Pies, Luke Moma, Aelin Kim, Hatice Basdag, Courtnee Rodgers, Satyajit Kosuri, Ryunosuke Saiki, Hideki Makishima, Sanjukta Tawde, Shelly Galasinski, Priscilla Kandikatla, Hari Prasanna Subramanian, Kehan Ren, Honghao Bi, Mona Mohammadhosseini, Seishi Ogawa, Peng Ji, Anupriya Agarwal, Soma Das, Lucy A. Godley

https://doi.org/10.3324/haematol.2024.286887

Myeloproliferative Disorders

Cytogenetic abnormalities in polycythemia vera: phenotypic correlates and prognostic relevance in 669 informative cases (1812 Online Views)

Moazah Iftikhar, Masooma Rana, Yamna Jadoon, Maymona Abdelmagid, Kaaren Reichard, Cinthya Zepeda Mendoza, Animesh Pardanani, Ayalew Tefferi, Naseema Gangat

https://doi.org/10.3324/haematol.2025.287569

Non-Hodgkin Lymphoma

Evorpacept plus rituximab for the treatment of relapsed or refractory non-Hodgkin lymphoma: results from the phase I ASPEN-01 study (2180 Online Views)

Tae Min Kim, Nehal J. Lakhani, Jacob Soumerai, Manali Kamdar, Justin F. Gainor, Wells Messersmith, Philip Fanning, Shanhong Guan, Feng Jin, Alison Forgie, Hong I. Wan, Jaume Pons, Sophia S. Randolph, Won Seog Kim

https://doi.org/10.3324/haematol.2024.286208

Plasma Cell Disorders

Outcomes and treatment patterns in primary and secondary plasma cell leukemia: insights from a large US cohort study (4475 Online Views)

Shagun Singh, Supriya Peshin, Betsy C. Wertheim, Ashley Larsen, Iloabueke Chineke, Douglas W. Sborov, Damian Green, Michaela Liedtke, Marie Okoniewski, Mohammed Wazir, Omar Nadeem, Levanto G. Schachter, Dominique DeGraaff, Victoria A. Vardell, David G. Coffey, Krisstina Gowin

https://doi.org/10.3324/haematol.2024.287158

Isatuximab plus bortezomib, lenalidomide, and dexamethasone for transplant-ineligible newly diagnosed multiple myeloma patients: a frailty subgroup analysis of the IMROZ trial (5472 Online Views)

Salomon Manier, Meletios-Athanasios Dimopoulos, Xavier P. Leleu, Philippe Moreau, Michele Cavo, Hartmut Goldschmidt, Robert Z. Orlowski, Muriel Tron, Christina Tekle, Marie-France Brégeault, Andrea T. Shafer, Meral Beksac, Thierry Facon

https://doi.org/10.3324/haematol.2024.287200

Early identification of functional high-risk multiple myeloma patients after transplant: the predictive power of fat fraction and Response Assessment Category score in diffusion-weighted whole-body magnetic resonance imaging (1743 Online Views)

Angelo Belotti, Barbara Frittoli, Sofia Terlizzi, Rossella Ribolla, Claudia Crippa, Chiara Saeli, Samantha Ferrari, Nicola Bianchetti, Chiara Bottelli, Chiara Cattaneo, Carmela Carbone, Alessandro Gullino, Marco Chiarini, Viviana Giustini, Aldo Roccaro, Luigi Grazioli, Alessandra Tucci

https://doi.org/10.3324/haematol.2025.287409

Prognostic value of minimal residual disease detected by EuroFlow next-generation flow cytometry and next-generation sequencing in patients with multiple myeloma achieving complete response and receiving lenalidomide maintenance after autotransplant: a prospective comparison study (2087 Online Views)

Takeshi Yoroidaka, Hiroyuki Takamatsu, Ryota Urushihara, Mitsuhiro Itagaki, Satoshi Yoshihara, Kota Sato, Naoki Takezako, Shuji Ozaki, Kazuhito Suzuki, Kentaro Kohno, Tsuyoshi Muta, Morio Matsumoto, Yasushi Terasaki, Takeshi Yamashita, Shin-ichi Fuchida, Jun Sakamoto, Tadao Ishida, Kenshi Suzuki, Hirokazu Murakami, Brian G.M. Durie, Kazuyuki Shimizu

https://doi.org/10.3324/haematol.2025.287411

Letters to the Editor

Genetic and clinical characteristics of patients with Shwachman Diamond syndrome with special consideration of treatment with granulocyte-colony stimulating factor (1839 Online Views)

Sabine Mellor-Heineke, Julia Skokowa, Natali Gerschmann, Ekaterina Deordieva, Ivan Tesakov, Sally Kinsey, Maja Klaudel-Dreszler, Piero Farruggia, Martina Sukova, Mikael Sundin, Yasmine El Chazli, Tania N. Masmas, Leen Willems, Georg Ebetsberger-Dachs, Hans C. Erichsen, Orna Steinberg-Shemer, Anna Shcherbina, Karl Welte, Cornelia Zeidler

https://doi.org/10.3324/haematol.2024.286119

Clonal hematopoiesis is common in bone marrow of patients with classical Hodgkin lymphoma (1835 Online Views)

Rebeca Iglesias, Eva Díaz, Sara Fernández, Marta Miguélez, María De Rosa Torres, Mirna L. Domínguez, José L. Solórzano, Mónica Estévez, Raquel Oña, Alejandro M. Bobes, Carlos Montalbán, Adolfo de la Fuente, Juan F. García

https://doi.org/10.3324/haematol.2024.286579

MAP-kinase mutations and aortic lesions are associated with distribution of circulating monocytes in histiocytosis (1352 Online Views)

Jerome Razanamahery, Helene Greigert, Matthias Papo, Jean-Francois Emile, Julien Guy, Francesco Pegoraro, Julien Haroche, Sylvain Audia, Maxime Samson, Bernard Bonnotte

https://doi.org/10.3324/haematol.2024.286716

Hematologic dysfunction and myeloid neoplasm risk in patients treated with lutetium-177 prostate-specific antigen membrane therapy (1582 Online Views)

Yael Kusne, Osama M. Mosalem, Jaxon Quillen, Skye Buckner-Petty, Miguel Muniz, Oliver Sartor, Geoffrey B. Johnson, Daniel S. Childs, Mrinal M. Patnaik

https://doi.org/10.3324/haematol.2024.286808

Venetoclax combined with escalating doses of homoharringtonine, low-dose cytarabine, and granulocyte colony-stimulating factor demonstrates feasibility and tolerability for remission induction in pediatric acute myeloid leukemia (1664 Online Views)

Shengqin Cheng, Li Gao, Jun Lu, Yixin Hu, Yi Wang, Hailong He, Jie Li, Suxiang Liu, Feiyun Yang, Xiaofang Wu, Liyan Fan, Junjie Fan, Yanhua Yao, Yina Sun, Bohan Li, Yongping Zhang, Shuiyan Wu, Cheng Cheng, Peifang Xiao, Raul C. Ribeiro, Hu Shaoyan

https://doi.org/10.3324/haematol.2024.286832

Dissecting CD47 expression in lymphoid neoplasms to inform precision immunotherapy with anti-CD47 phagocytic checkpoint blockade (2181 Online Views)

Andrea Marra, Alan Ramsay, Samuel Chamberlain-Keene, Gabriela Soares, Maurilio Ponzoni, Sugerdana Padmasri, Manuel Rodriguez-Justo, Sabine Pomplun, Ian Proctor, Anna Childerhouse, Alsharabati Muntasser, Mario Cioce, Vito Michele Fazio, German Ott, Miguel Piris, Brunangelo Falini, Teresa Marafioti

https://doi.org/10.3324/haematol.2024.286864

Doubling in median survival in patients diagnosed with multiple myeloma 2005-2019; a real-world study from the UK’s Haematological Malignancy Research Network (2441 Online Views)

Alexandra Smith, Timothy Bagguley, Eve Roman, Simon Crouch, Russell Patmore, Ruth De Tute, Andy Rawstron, Gordon Cook, Frances Seymour, Christopher Parrish

https://doi.org/10.3324/haematol.2024.287095

Clonal hematopoiesis of indeterminate potential associates with higher risk of thromboembolism in severe COVID-19 (1587 Online Views)

Gregorio Maria Bergonzi, Jacques-Emmanuel Galimard, Federico Mario Aletti, Piera Angelillo, Sara Mastaglio, Federico Erbella, Diego Palumbo, Giliola Calori, Patrizia Rovere Querini, Cristina Tresoldi, Gabriele Fragasso, Francesco De Cobelli, Andrea Angelo Assanelli, Fabio Ciceri, Matteo G. Della Porta, Annalisa Ruggeri, Massimo Bernardi

https://doi.org/10.3324/haematol.2024.287128

Predictors of response to pacritinib therapy and survival among 60 Mayo Clinic patients with myelofibrosis treated outside of clinical trials (1733 Online Views)

Maymona Abdelmagid, Jeanne M. Palmer, Aref Al-Kali, Mehrdad Hefazi, James Foran, Kebede H. Begna, Cecilia Y. Arana Yi, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi

https://doi.org/10.3324/haematol.2025.287576

Case Reports

Marginal zone lymphoma with anti-factor H IgM and atypical hemolytic uremic syndrome successfully treated with odronextamab (1559 Online Views)

Gianluigi Ardissino, Piera Angelillo, Maria Cristina Mancuso, Samantha Griffini, Elena Grovetti, Luigi Porcaro, Thomas Ria, Sarah Marktel, Flora Peyvandi, Stefano Luminari, Andrés J.M. Ferreri, Michele Merli, Massimo Cugno

https://doi.org/10.3324/haematol.2025.287532

Acquired Bernard-Soulier syndrome as the presenting feature of GATA2-related myeloid neoplasm in an adolescent: an insight into the mechanisms underlying the platelet defect (1427 Online Views)

Laureano J. Kamiya, María D. Morell, Rosana F. Marta, Marina Narbaitz, Christophe Marzac, Nora P. Goette, Geraldine De Luca, Paola R. Lev, María F. Metrebian, Daiana Ganiewich, Andrea S. Llera, Hana Raslova, Paula G. Heller, Ana C. Glembotsky

https://doi.org/10.3324/haematol.2025.287580